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2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.
Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J. Fu X, et al. Among authors: fazlollahi f. Cell Metab. 2015 Sep 1;22(3):508-15. doi: 10.1016/j.cmet.2015.06.009. Epub 2015 Jul 16. Cell Metab. 2015. PMID: 26190651 Free PMC article.
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.
Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. Chin RM, et al. Among authors: fazlollahi f. Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14. Nature. 2014. PMID: 24828042 Free PMC article.
Metabolomic analysis of cerebral spinal fluid from patients with severe brain injury.
Glenn TC, Hirt D, Mendez G, McArthur DL, Sturtevant R, Wolahan S, Fazlollahi F, Ordon M, Bilgin-Freiert A, Ellingson B, Vespa P, Hovda DA, Martin NA. Glenn TC, et al. Among authors: fazlollahi f. Acta Neurochir Suppl. 2013;118:115-9. doi: 10.1007/978-3-7091-1434-6_20. Acta Neurochir Suppl. 2013. PMID: 23564115
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium.
Mashali MA, Saad NS, Canan BD, Elnakish MT, Milani-Nejad N, Chung JH, Schultz EJ, Kiduko SA, Huang AW, Hare AN, Peczkowski KK, Fazlollahi F, Martin BL, Murray JD, Campbell CM, Kilic A, Whitson BA, Mokadam NA, Mohler PJ, Janssen PML. Mashali MA, et al. Among authors: fazlollahi f. J Mol Cell Cardiol. 2021 Jul;156:7-19. doi: 10.1016/j.yjmcc.2021.03.007. Epub 2021 Mar 22. J Mol Cell Cardiol. 2021. PMID: 33766524 Free PMC article.
20 results