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Page 1
17β-Hydroxysteroid Dehydrogenase Type 2 Inhibition: Discovery of Selective and Metabolically Stable Compounds Inhibiting Both the Human Enzyme and Its Murine Ortholog.
Gargano EM, Allegretta G, Perspicace E, Carotti A, Van Koppen C, Frotscher M, Marchais-Oberwinkler S, Hartmann RW. Gargano EM, et al. Among authors: allegretta g. PLoS One. 2015 Jul 31;10(7):e0134754. doi: 10.1371/journal.pone.0134754. eCollection 2015. PLoS One. 2015. PMID: 26230928 Free PMC article.
CYP17A1-independent production of the neurosteroid-derived 5α-pregnan-3β,6α-diol-20-one in androgen-responsive prostate cancer cell lines under serum starvation and inhibition by Abiraterone.
de Mello Martins AGG, Allegretta G, Unteregger G, Haupenthal J, Eberhard J, Hoffmann M, van der Zee JA, Junker K, Stöckle M, Müller R, Hartmann RW, Ohlmann CH. de Mello Martins AGG, et al. Among authors: allegretta g. J Steroid Biochem Mol Biol. 2017 Nov;174:183-191. doi: 10.1016/j.jsbmb.2017.09.006. Epub 2017 Sep 7. J Steroid Biochem Mol Biol. 2017. PMID: 28890368
In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics.
Graef F, Richter R, Fetz V, Murgia X, De Rossi C, Schneider-Daum N, Allegretta G, Elgaher W, Haupenthal J, Empting M, Beckmann F, Brönstrup M, Hartmann R, Gordon S, Lehr CM. Graef F, et al. Among authors: allegretta g. ACS Infect Dis. 2018 Aug 10;4(8):1188-1196. doi: 10.1021/acsinfecdis.7b00165. Epub 2018 May 24. ACS Infect Dis. 2018. PMID: 29750862
Exploration of the Structural Space in 4(3H)-Quinazolinone Antibacterials.
Qian Y, Allegretta G, Janardhanan J, Peng Z, Mahasenan KV, Lastochkin E, Gozun MMN, Tejera S, Schroeder VA, Wolter WR, Feltzer R, Mobashery S, Chang M. Qian Y, et al. Among authors: allegretta g. J Med Chem. 2020 May 28;63(10):5287-5296. doi: 10.1021/acs.jmedchem.0c00153. Epub 2020 May 8. J Med Chem. 2020. PMID: 32343145 Free PMC article.
12 results