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Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes.
Fougerat A, Gayral S, Gourdy P, Schambourg A, Rückle T, Schwarz MK, Rommel C, Hirsch E, Arnal JF, Salles JP, Perret B, Breton-Douillon M, Wymann MP, Laffargue M. Fougerat A, et al. Among authors: gayral s. Circulation. 2008 Mar 11;117(10):1310-7. doi: 10.1161/CIRCULATIONAHA.107.720466. Epub 2008 Feb 11. Circulation. 2008. PMID: 18268153
Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response.
Smirnova NF, Gayral S, Pedros C, Loirand G, Vaillant N, Malet N, Kassem S, Calise D, Goudounèche D, Wymann MP, Hirsch E, Gadeau AP, Martinez LO, Saoudi A, Laffargue M. Smirnova NF, et al. Among authors: gayral s. J Exp Med. 2014 Aug 25;211(9):1779-92. doi: 10.1084/jem.20131276. Epub 2014 Jul 29. J Exp Med. 2014. PMID: 25073791 Free PMC article.
Matrix ageing and vascular impacts: focus on elastin fragmentation.
Duca L, Blaise S, Romier B, Laffargue M, Gayral S, El Btaouri H, Kawecki C, Guillot A, Martiny L, Debelle L, Maurice P. Duca L, et al. Among authors: gayral s. Cardiovasc Res. 2016 Jun 1;110(3):298-308. doi: 10.1093/cvr/cvw061. Epub 2016 Mar 22. Cardiovasc Res. 2016. PMID: 27009176 Review.
28 results