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Page 1
Efavirenz modulation of sleep spindles and sleep spectral profile.
Simen AA, Ma J, Svetnik V, Mayleben D, Maynard J, Roth A, Mixson L, Mogg R, Shera D, George L, Mast TC, Beals C, Stoch A, Struyk A, Shire N, Fraser I. Simen AA, et al. J Sleep Res. 2015 Feb;24(1):66-73. doi: 10.1111/jsr.12196. Epub 2014 Aug 12. J Sleep Res. 2015. PMID: 25113527 Clinical Trial.
An Acetylcholine M1 Receptor-Positive Allosteric Modulator (TAK-071) in Parkinson Disease With Cognitive Impairment: A Phase 2 Randomized Clinical Trial.
Shanbhag NM, Padmanabhan JL, Zhang Z, Harel BT, Jia H, Kangarloo T, Yin W, Dowling AV, Laurenza A, Khudyakov P, Galinsky K, Latzman RD, Simuni T, Weintraub D, Horak FB, Lustig C, Maruff P, Simen AA. Shanbhag NM, et al. Among authors: simen aa. JAMA Neurol. 2025 Jan 6. doi: 10.1001/jamaneurol.2024.4519. Online ahead of print. JAMA Neurol. 2025. PMID: 39761063
Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.
Beckman D, Diniz GB, Ott S, Hobson B, Chaudhari AJ, Muller S, Chu Y, Takano A, Schwarz AJ, Yeh CL, McQuade P, Chakrabarty P, Kanaan NM, Quinton MS, Simen AA, Kordower JH, Morrison JH. Beckman D, et al. Among authors: simen aa. Alzheimers Dement. 2024 Aug;20(8):5198-5219. doi: 10.1002/alz.13868. Epub 2024 Jun 21. Alzheimers Dement. 2024. PMID: 39030748 Free PMC article.
cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex.
Carlyle BC, Nairn AC, Wang M, Yang Y, Jin LE, Simen AA, Ramos BP, Bordner KA, Craft GE, Davies P, Pletikos M, Šestan N, Arnsten AF, Paspalas CD. Carlyle BC, et al. Among authors: simen aa. Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):5036-41. doi: 10.1073/pnas.1322360111. Epub 2014 Mar 18. Proc Natl Acad Sci U S A. 2014. PMID: 24707050 Free PMC article.
Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels.
El-Hassar L, Simen AA, Duque A, Patel KD, Kaczmarek LK, Arnsten AF, Yeckel MF. El-Hassar L, et al. Among authors: simen aa. Biol Psychiatry. 2014 Sep 15;76(6):476-85. doi: 10.1016/j.biopsych.2013.12.019. Epub 2014 Jan 20. Biol Psychiatry. 2014. PMID: 24560582 Free PMC article.
37 results