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Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Bajda M, Jończyk J, Malawska B, Czarnecka K, Girek M, Olszewska P, Sikora J, Mikiciuk-Olasik E, Skibiński R, Gumieniczek A, Szymański P. Bajda M, et al. Among authors: jonczyk j. Bioorg Med Chem. 2015 Sep 1;23(17):5610-8. doi: 10.1016/j.bmc.2015.07.029. Epub 2015 Jul 21. Bioorg Med Chem. 2015. PMID: 26242241
Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.
Lodarski K, Jończyk J, Guzior N, Bajda M, Gładysz J, Walczyk J, Jeleń M, Morak-Młodawska B, Pluta K, Malawska B. Lodarski K, et al. Among authors: jonczyk j. J Enzyme Inhib Med Chem. 2015 Feb;30(1):98-106. doi: 10.3109/14756366.2014.889127. Epub 2014 Mar 25. J Enzyme Inhib Med Chem. 2015. PMID: 24666296 Free article.
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.
Panek D, Więckowska A, Wichur T, Bajda M, Godyń J, Jończyk J, Mika K, Janockova J, Soukup O, Knez D, Korabecny J, Gobec S, Malawska B. Panek D, et al. Among authors: jonczyk j. Eur J Med Chem. 2017 Jan 5;125:676-695. doi: 10.1016/j.ejmech.2016.09.078. Epub 2016 Sep 26. Eur J Med Chem. 2017. PMID: 27721153
51 results