Wong PC - Search Results

1

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.

Ling JP, Pletnikova O, Troncoso JC, Wong PC. Ling JP, et al. Among authors: wong pc. Science. 2015 Aug 7;349(6248):650-5. doi: 10.1126/science.aab0983. Science. 2015. PMID: 26250685 Free PMC article.

2

Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.

Chiang PM, Ling J, Jeong YH, Price DL, Aja SM, Wong PC. Chiang PM, et al. Among authors: wong pc. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16320-4. doi: 10.1073/pnas.1002176107. Epub 2010 Jul 26. Proc Natl Acad Sci U S A. 2010. PMID: 20660762 Free PMC article.

3

Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.

Wu J, Petralia RS, Kurushima H, Patel H, Jung MY, Volk L, Chowdhury S, Shepherd JD, Dehoff M, Li Y, Kuhl D, Huganir RL, Price DL, Scannevin R, Troncoso JC, Wong PC, Worley PF. Wu J, et al. Among authors: wong pc. Cell. 2011 Oct 28;147(3):615-28. doi: 10.1016/j.cell.2011.09.036. Cell. 2011. PMID: 22036569 Free PMC article.

4

Rodent models of TDP-43: recent advances.

Tsao W, Jeong YH, Lin S, Ling J, Price DL, Chiang PM, Wong PC. Tsao W, et al. Among authors: wong pc. Brain Res. 2012 Jun 26;1462:26-39. doi: 10.1016/j.brainres.2012.04.031. Epub 2012 May 1. Brain Res. 2012. PMID: 22608070 Free PMC article. Review.

5

Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.

LaClair KD, Manaye KF, Lee DL, Allard JS, Savonenko AV, Troncoso JC, Wong PC. LaClair KD, et al. Among authors: wong pc. Mol Neurodegener. 2013 Jun 13;8:18. doi: 10.1186/1750-1326-8-18. Mol Neurodegener. 2013. PMID: 23764200 Free PMC article.

6

Altered astrocytic expression of TDP-43 does not influence motor neuron survival.

Haidet-Phillips AM, Gross SK, Williams T, Tuteja A, Sherman A, Ko M, Jeong YH, Wong PC, Maragakis NJ. Haidet-Phillips AM, et al. Among authors: wong pc. Exp Neurol. 2013 Dec;250:250-9. doi: 10.1016/j.expneurol.2013.10.004. Epub 2013 Oct 9. Exp Neurol. 2013. PMID: 24120466

7

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.

Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. Freibaum BD, et al. Among authors: wong pc. Nature. 2015 Sep 3;525(7567):129-33. doi: 10.1038/nature14974. Epub 2015 Aug 26. Nature. 2015. PMID: 26308899 Free PMC article.

8

PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.

Ling JP, Chhabra R, Merran JD, Schaughency PM, Wheelan SJ, Corden JL, Wong PC. Ling JP, et al. Among authors: wong pc. Cell Rep. 2016 Sep 27;17(1):104-113. doi: 10.1016/j.celrep.2016.08.071. Cell Rep. 2016. PMID: 27681424 Free PMC article.

9

Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.

LaClair KD, Donde A, Ling JP, Jeong YH, Chhabra R, Martin LJ, Wong PC. LaClair KD, et al. Among authors: wong pc. Acta Neuropathol. 2016 Dec;132(6):859-873. doi: 10.1007/s00401-016-1637-y. Epub 2016 Oct 26. Acta Neuropathol. 2016. PMID: 27785573 Free PMC article.

10

Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.

Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, Wong PC, Monteiro MJ. Le NT, et al. Among authors: wong pc. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7580-E7589. doi: 10.1073/pnas.1608432113. Epub 2016 Nov 9. Proc Natl Acad Sci U S A. 2016. PMID: 27834214 Free PMC article.

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