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Page 1
β2-Adrenergic receptor agonists activate CFTR in intestinal organoids and subjects with cystic fibrosis.
Vijftigschild LA, Berkers G, Dekkers JF, Zomer-van Ommen DD, Matthes E, Kruisselbrink E, Vonk A, Hensen CE, Heida-Michel S, Geerdink M, Janssens HM, van de Graaf EA, Bronsveld I, de Winter-de Groot KM, Majoor CJ, Heijerman HG, de Jonge HR, Hanrahan JW, van der Ent CK, Beekman JM. Vijftigschild LA, et al. Eur Respir J. 2016 Sep;48(3):768-79. doi: 10.1183/13993003.01661-2015. Epub 2016 Jul 28. Eur Respir J. 2016. PMID: 27471203 Free article. Clinical Trial.
CFTR-mutation specific applications of CFTR-directed monoclonal antibodies.
van Meegen MA, Terheggen SW, Koymans KJ, Vijftigschild LA, Dekkers JF, van der Ent CK, Beekman JM. van Meegen MA, et al. Among authors: vijftigschild la. J Cyst Fibros. 2013 Sep;12(5):487-96. doi: 10.1016/j.jcf.2012.12.005. Epub 2013 Jan 11. J Cyst Fibros. 2013. PMID: 23317763 Free article.
A bioassay using intestinal organoids to measure CFTR modulators in human plasma.
Dekkers R, Vijftigschild LA, Vonk AM, Kruisselbrink E, de Winter-de Groot KM, Janssens HM, van der Ent CK, Beekman JM. Dekkers R, et al. Among authors: vijftigschild la. J Cyst Fibros. 2015 Mar;14(2):178-81. doi: 10.1016/j.jcf.2014.10.007. Epub 2014 Nov 6. J Cyst Fibros. 2015. PMID: 25467948 Free article.
Cell-penetrating bisubstrate-based protein kinase C inhibitors.
van Wandelen LT, van Ameijde J, Ismail-Ali AF, van Ufford HC, Vijftigschild LA, Beekman JM, Martin NI, Ruijtenbeek R, Liskamp RM. van Wandelen LT, et al. Among authors: vijftigschild la. ACS Chem Biol. 2013 Jul 19;8(7):1479-87. doi: 10.1021/cb300709g. Epub 2013 May 8. ACS Chem Biol. 2013. PMID: 23621550