Hu W - Search Results

1

BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function.

Yue X, Zhao Y, Liu J, Zhang C, Yu H, Wang J, Zheng T, Liu L, Li J, Feng Z, Hu W. Yue X, et al. Among authors: hu w. Elife. 2015 Aug 13;4:e08401. doi: 10.7554/eLife.08401. Elife. 2015. PMID: 26271008 Free PMC article.

2

Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms.

Hu W, Feng Z, Tang MS. Hu W, et al. Biochemistry. 2003 Aug 26;42(33):10012-23. doi: 10.1021/bi034631s. Biochemistry. 2003. PMID: 12924950

3

Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis.

Feng Z, Hu W, Tang MS. Feng Z, et al. Among authors: hu w. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8598-602. doi: 10.1073/pnas.0402794101. Proc Natl Acad Sci U S A. 2004. PMID: 15187227 Free PMC article.

4

Chromium(VI) enhances (+/-)-anti-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced cytotoxicity and mutagenicity in mammalian cells through its inhibitory effect on nucleotide excision repair.

Hu W, Feng Z, Tang MS. Hu W, et al. Biochemistry. 2004 Nov 9;43(44):14282-9. doi: 10.1021/bi048560o. Biochemistry. 2004. PMID: 15518579

5

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.

Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Arva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P, Onel K, Yip L, Hwang SJ, Strong LC, Lozano G, Levine AJ. Bond GL, et al. Among authors: hu w. Cell. 2004 Nov 24;119(5):591-602. doi: 10.1016/j.cell.2004.11.022. Cell. 2004. PMID: 15550242 Free article.

6

Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair.

Feng Z, Hu W, Hu Y, Tang MS. Feng Z, et al. Among authors: hu w, hu y. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15404-9. doi: 10.1073/pnas.0607031103. Epub 2006 Oct 9. Proc Natl Acad Sci U S A. 2006. PMID: 17030796 Free PMC article.

7

A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells.

Hu W, Feng Z, Ma L, Wagner J, Rice JJ, Stolovitzky G, Levine AJ. Hu W, et al. Cancer Res. 2007 Mar 15;67(6):2757-65. doi: 10.1158/0008-5472.CAN-06-2656. Cancer Res. 2007. PMID: 17363597

8

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways.

Feng Z, Hu W, de Stanchina E, Teresky AK, Jin S, Lowe S, Levine AJ. Feng Z, et al. Among authors: hu w. Cancer Res. 2007 Apr 1;67(7):3043-53. doi: 10.1158/0008-5472.CAN-06-4149. Cancer Res. 2007. PMID: 17409411

9

Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations.

Feng Z, Hu W, Teresky AK, Hernando E, Cordon-Cardo C, Levine AJ. Feng Z, et al. Among authors: hu w. Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16633-8. doi: 10.1073/pnas.0708043104. Epub 2007 Oct 5. Proc Natl Acad Sci U S A. 2007. PMID: 17921246 Free PMC article.

10

p53 regulates maternal reproduction through LIF.

Hu W, Feng Z, Teresky AK, Levine AJ. Hu W, et al. Nature. 2007 Nov 29;450(7170):721-4. doi: 10.1038/nature05993. Nature. 2007. PMID: 18046411

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