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HSP90 Inhibitor-SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors.
Proia DA, Smith DL, Zhang J, Jimenez JP, Sang J, Ogawa LS, Sequeira M, Acquaviva J, He S, Zhang C, Khazak V, Astsaturov I, Inoue T, Tatsuta N, Osman S, Bates RC, Chimmanamada D, Ying W. Proia DA, et al. Among authors: chimmanamada d. Mol Cancer Ther. 2015 Nov;14(11):2422-32. doi: 10.1158/1535-7163.MCT-15-0455. Epub 2015 Aug 13. Mol Cancer Ther. 2015. PMID: 26271675
Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.
Seeger-Nukpezah T, Proia DA, Egleston BL, Nikonova AS, Kent T, Cai KQ, Hensley HH, Ying W, Chimmanamada D, Serebriiskii IG, Golemis EA. Seeger-Nukpezah T, et al. Among authors: chimmanamada d. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12786-91. doi: 10.1073/pnas.1301904110. Epub 2013 Jul 15. Proc Natl Acad Sci U S A. 2013. PMID: 23858461 Free PMC article.
Potent anti-muscarinic activity in a novel series of quinuclidine derivatives.
Starck JP, Talaga P, Quéré L, Collart P, Christophe B, Lo Brutto P, Jadot S, Chimmanamada D, Zanda M, Wagner A, Mioskowski C, Massingham R, Guyaux M. Starck JP, et al. Among authors: chimmanamada d. Bioorg Med Chem Lett. 2006 Jan 15;16(2):373-7. doi: 10.1016/j.bmcl.2005.09.079. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275087