Holliger P - Search Results

1

A polymerase engineered for bisulfite sequencing.

Millar D, Christova Y, Holliger P. Millar D, et al. Among authors: holliger p. Nucleic Acids Res. 2015 Dec 15;43(22):e155. doi: 10.1093/nar/gkv798. Epub 2015 Aug 13. Nucleic Acids Res. 2015. PMID: 26271989 Free PMC article.

2

Autocrine costimulation: tumor-specific CD28-mediated costimulation of T cells by in situ production of a bifunctional B7-anti-CEA diabody fusion protein.

Blanco B, Holliger P, Alvarez-Vallina L. Blanco B, et al. Among authors: holliger p. Cancer Gene Ther. 2002 Mar;9(3):275-81. doi: 10.1038/sj.cgt.7700438. Cancer Gene Ther. 2002. PMID: 11896444

3

Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution.

Ghadessy FJ, Ramsay N, Boudsocq F, Loakes D, Brown A, Iwai S, Vaisman A, Woodgate R, Holliger P. Ghadessy FJ, et al. Among authors: holliger p. Nat Biotechnol. 2004 Jun;22(6):755-9. doi: 10.1038/nbt974. Epub 2004 May 23. Nat Biotechnol. 2004. PMID: 15156154

4

Directed evolution of DNA polymerase, RNA polymerase and reverse transcriptase activity in a single polypeptide.

Ong JL, Loakes D, Jaroslawski S, Too K, Holliger P. Ong JL, et al. Among authors: holliger p. J Mol Biol. 2006 Aug 18;361(3):537-50. doi: 10.1016/j.jmb.2006.06.050. Epub 2006 Jul 5. J Mol Biol. 2006. PMID: 16859707

5

Compartmentalized self-replication: a novel method for the directed evolution of polymerases and other enzymes.

Ghadessy FJ, Holliger P. Ghadessy FJ, et al. Among authors: holliger p. Methods Mol Biol. 2007;352:237-48. doi: 10.1385/1-59745-187-8:237. Methods Mol Biol. 2007. PMID: 17041269

6

Molecular breeding of polymerases for amplification of ancient DNA.

d'Abbadie M, Hofreiter M, Vaisman A, Loakes D, Gasparutto D, Cadet J, Woodgate R, Pääbo S, Holliger P. d'Abbadie M, et al. Among authors: holliger p. Nat Biotechnol. 2007 Aug;25(8):939-43. doi: 10.1038/nbt1321. Epub 2007 Jul 15. Nat Biotechnol. 2007. PMID: 17632524 Free PMC article.

7

Evolving a polymerase for hydrophobic base analogues.

Loakes D, Gallego J, Pinheiro VB, Kool ET, Holliger P. Loakes D, et al. Among authors: holliger p. J Am Chem Soc. 2009 Oct 21;131(41):14827-37. doi: 10.1021/ja9039696. J Am Chem Soc. 2009. PMID: 19778048 Free PMC article.

8

CyDNA: synthesis and replication of highly Cy-dye substituted DNA by an evolved polymerase.

Ramsay N, Jemth AS, Brown A, Crampton N, Dear P, Holliger P. Ramsay N, et al. Among authors: holliger p. J Am Chem Soc. 2010 Apr 14;132(14):5096-104. doi: 10.1021/ja909180c. J Am Chem Soc. 2010. PMID: 20235594 Free PMC article.

9

Molecular breeding of polymerases for resistance to environmental inhibitors.

Baar C, d'Abbadie M, Vaisman A, Arana ME, Hofreiter M, Woodgate R, Kunkel TA, Holliger P. Baar C, et al. Among authors: holliger p. Nucleic Acids Res. 2011 Apr;39(8):e51. doi: 10.1093/nar/gkq1360. Epub 2011 Feb 4. Nucleic Acids Res. 2011. PMID: 21297114 Free PMC article.

10

Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering.

Houlihan G, Arangundy-Franklin S, Holliger P. Houlihan G, et al. Among authors: holliger p. Acc Chem Res. 2017 Apr 18;50(4):1079-1087. doi: 10.1021/acs.accounts.7b00056. Epub 2017 Apr 6. Acc Chem Res. 2017. PMID: 28383245 Free PMC article. Review.

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