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Page 1
Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.
Engel J, Richters A, Getlik M, Tomassi S, Keul M, Termathe M, Lategahn J, Becker C, Mayer-Wrangowski S, Grütter C, Uhlenbrock N, Krüll J, Schaumann N, Eppmann S, Kibies P, Hoffgaard F, Heil J, Menninger S, Ortiz-Cuaran S, Heuckmann JM, Tinnefeld V, Zahedi RP, Sos ML, Schultz-Fademrecht C, Thomas RK, Kast SM, Rauh D. Engel J, et al. Among authors: krull j. J Med Chem. 2015 Sep 10;58(17):6844-63. doi: 10.1021/acs.jmedchem.5b01082. Epub 2015 Aug 31. J Med Chem. 2015. PMID: 26275028
Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.
Kaitsiotou H, Keul M, Hardick J, Mühlenberg T, Ketzer J, Ehrt C, Krüll J, Medda F, Koch O, Giordanetto F, Bauer S, Rauh D. Kaitsiotou H, et al. Among authors: krull j. J Med Chem. 2017 Nov 9;60(21):8801-8815. doi: 10.1021/acs.jmedchem.7b00841. Epub 2017 Oct 24. J Med Chem. 2017. PMID: 28991465
Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment.
Yeo YY, Chang Y, Qiu H, Yiu SPT, Michel HA, Wu W, Jin X, Kure S, Parmelee L, Luo S, Cramer P, Lee JL, Wang Y, Yeung J, Ahmar NE, Simsek B, Mohanna R, Van Orden M, Lu W, Livak KJ, Li S, Shahryari J, Kingsley L, Al-Humadi RN, Nasr S, Nkosi D, Sadigh S, Rock P, Frauenfeld L, Kaufmann L, Zhu B, Basak A, Dhanikonda N, Chan CN, Krull J, Cho YW, Chen CY, Lee JYJ, Wang H, Zhao B, Loo LH, Kim DM, Boussiotis V, Zhang B, Shalek AK, Howitt B, Signoretti S, Schürch CM, Hodi FS, Burack WR, Rodig SJ, Ma Q, Jiang S. Yeo YY, et al. Among authors: krull j. bioRxiv [Preprint]. 2024 Dec 22:2024.12.20.629650. doi: 10.1101/2024.12.20.629650. bioRxiv. 2024. PMID: 39764057 Free PMC article. Preprint.
Expanded tumor-associated polymorphonuclear myeloid-derived suppressor cells in Waldenstrom macroglobulinemia display immune suppressive activity.
Bhardwaj V, Yang ZZ, Jalali S, Villasboas JC, Mudappathi R, Wang J, Mukherjee P, Paludo J, Tang X, Kim HJ, Krull JE, Wenzl K, Novak AJ, Mondello P, Ansell SM. Bhardwaj V, et al. Among authors: krull je. Blood Cancer J. 2024 Dec 18;14(1):217. doi: 10.1038/s41408-024-01173-w. Blood Cancer J. 2024. PMID: 39695096 Free PMC article.
Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system.
Adameyko I, Bakken T, Bhaduri A, Chhatbar C, Filbin MG, Gate D, Hochgerner H, Kim CN, Krull J, La Manno G, Li Q, Linnarsson S, Ma Q, Mayer C, Menon V, Nano P, Prinz M, Quake S, Walsh CA, Yang J, Bayraktar OA, Gokce O, Habib N, Konopka G, Liddelow SA, Nowakowski TJ. Adameyko I, et al. Among authors: krull j. Nat Neurosci. 2024 Dec;27(12):2278-2291. doi: 10.1038/s41593-024-01827-9. Epub 2024 Dec 3. Nat Neurosci. 2024. PMID: 39627588 Review.
Molecular Features of Diffuse Large B-Cell Lymphoma Associated With Primary Treatment Resistance.
Bock AM, Wenzl K, Novak JP, Stokes ME, Hopper MA, Krull JE, Dropik AR, Sarangi V, Ortiz M, Stong N, Huang CC, Maurer MJ, King RL, Farooq U, Wang Y, Witzig TE, Ansell SM, Habermann TM, Cerhan JR, Gandhi AK, Nowakowski G, Novak AJ. Bock AM, et al. Among authors: krull je. Hematol Oncol. 2025 Jan;43(1):e70006. doi: 10.1002/hon.70006. Hematol Oncol. 2025. PMID: 39612356 Free PMC article.
DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas.
Hopper MA, Dropik AR, Walker JS, Novak JP, Laverty MS, Manske MK, Wu X, Wenzl K, Krull JE, Sarangi V, Maurer MJ, Yang ZZ, Del Busso MD, Habermann TM, Link BK, Rimsza LM, Witzig TE, Ansell SM, Cerhan JR, Jevremovic D, Novak AJ. Hopper MA, et al. Among authors: krull je. Blood Cancer J. 2024 Oct 9;14(1):172. doi: 10.1038/s41408-024-01145-0. Blood Cancer J. 2024. PMID: 39384745 Free PMC article.
121 results