Winckler T - Search Results

1

Evaluation of Homobivalent Carbolines as Designed Multiple Ligands for the Treatment of Neurodegenerative Disorders.

Otto R, Penzis R, Gaube F, Adolph O, Föhr KJ, Warncke P, Robaa D, Appenroth D, Fleck C, Enzensperger C, Lehmann J, Winckler T. Otto R, et al. Among authors: winckler t. J Med Chem. 2015 Aug 27;58(16):6710-5. doi: 10.1021/acs.jmedchem.5b00958. Epub 2015 Aug 17. J Med Chem. 2015. PMID: 26278660

2

Beta and gamma carboline derivatives as potential anti-Alzheimer agents: A comparison.

Otto R, Penzis R, Gaube F, Winckler T, Appenroth D, Fleck C, Tränkle C, Lehmann J, Enzensperger C. Otto R, et al. Among authors: winckler t. Eur J Med Chem. 2014 Nov 24;87:63-70. doi: 10.1016/j.ejmech.2014.09.048. Epub 2014 Sep 16. Eur J Med Chem. 2014. PMID: 25240096

3

Enantiomerically Pure 2-Methyltetrahydro-3-benzazepin-1-ols Selectively Blocking GluN2B Subunit Containing N-Methyl-D-aspartate Receptors.

Tewes B, Frehland B, Schepmann D, Robaa D, Uengwetwanit T, Gaube F, Winckler T, Sippl W, Wünsch B. Tewes B, et al. Among authors: winckler t. J Med Chem. 2015 Aug 13;58(15):6293-305. doi: 10.1021/acs.jmedchem.5b00897. Epub 2015 Jul 30. J Med Chem. 2015. PMID: 26186074

4

Evaluation of γ-carboline-phenothiazine conjugates as simultaneous NMDA receptor blockers and cholinesterase inhibitors.

Schwarthoff S, Tischer N, Sager H, Schätz B, Rohrbach MM, Raztsou I, Robaa D, Gaube F, Arndt HD, Winckler T. Schwarthoff S, et al. Among authors: winckler t. Bioorg Med Chem. 2021 Sep 15;46:116355. doi: 10.1016/j.bmc.2021.116355. Epub 2021 Aug 8. Bioorg Med Chem. 2021. PMID: 34391122

5

Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.

Rook Y, Schmidtke KU, Gaube F, Schepmann D, Wünsch B, Heilmann J, Lehmann J, Winckler T. Rook Y, et al. Among authors: winckler t. J Med Chem. 2010 May 13;53(9):3611-7. doi: 10.1021/jm1000024. J Med Chem. 2010. PMID: 20361801

6

Developmental gene regulation by an ancient intercellular communication system in social amoebae.

Asghar A, Groth M, Siol O, Gaube F, Enzensperger C, Glöckner G, Winckler T. Asghar A, et al. Among authors: winckler t. Protist. 2012 Jan;163(1):25-37. doi: 10.1016/j.protis.2010.12.002. Epub 2011 Mar 2. Protist. 2012. PMID: 21371934

7

1-Benzyl-1,2,3,4-tetrahydro-β-carboline as channel blocker of N-methyl-D-aspartate receptors.

Espinoza-Moraga M, Caballero J, Gaube F, Winckler T, Santos LS. Espinoza-Moraga M, et al. Among authors: winckler t. Chem Biol Drug Des. 2012 Apr;79(4):594-9. doi: 10.1111/j.1747-0285.2012.01317.x. Epub 2012 Feb 1. Chem Biol Drug Des. 2012. PMID: 22226015

8

A host factor supports retrotransposition of the TRE5-A population in Dictyostelium cells by suppressing an Argonaute protein.

Schmith A, Spaller T, Gaube F, Fransson Å, Boesler B, Ojha S, Nellen W, Hammann C, Söderbom F, Winckler T. Schmith A, et al. Among authors: winckler t. Mob DNA. 2015 Sep 3;6:14. doi: 10.1186/s13100-015-0045-5. eCollection 2015. Mob DNA. 2015. PMID: 26339297 Free PMC article.

9

Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols.

Tewes B, Frehland B, Schepmann D, Schmidtke KU, Winckler T, Wünsch B. Tewes B, et al. Among authors: winckler t. Bioorg Med Chem. 2010 Nov 15;18(22):8005-15. doi: 10.1016/j.bmc.2010.09.026. Epub 2010 Sep 24. Bioorg Med Chem. 2010. PMID: 20965739

10

Synthesis and biological evaluation of cycloalkylidene carboxylic acids as novel effectors of Ras/Raf interaction.

Friese A, Hell-Momeni K, Zündorf I, Winckler T, Dingermann T, Dannhardt G. Friese A, et al. Among authors: winckler t. J Med Chem. 2002 Mar 28;45(7):1535-42. doi: 10.1021/jm011101q. J Med Chem. 2002. PMID: 11906294

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