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Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms.
Wan H, Schroeder GM, Hart AC, Inghrim J, Grebinski J, Tokarski JS, Lorenzi MV, You D, Mcdevitt T, Penhallow B, Vuppugalla R, Zhang Y, Gu X, Iyer R, Lombardo LJ, Trainor GL, Ruepp S, Lippy J, Blat Y, Sack JS, Khan JA, Stefanski K, Sleczka B, Mathur A, Sun JH, Wong MK, Wu DR, Li P, Gupta A, Arunachalam PN, Pragalathan B, Narayanan S, K C N, Kuppusamy P, Purandare AV. Wan H, et al. Among authors: kuppusamy p. ACS Med Chem Lett. 2015 Jul 12;6(8):850-5. doi: 10.1021/acsmedchemlett.5b00226. eCollection 2015 Aug 13. ACS Med Chem Lett. 2015. PMID: 26288683 Free PMC article.
Design, synthesis and biological evaluation of phenol-linked uncialamycin antibody-drug conjugates.
Poudel YB, Rao C, Kotapati S, Deshpande M, Thevanayagam L, Pan C, Cardarelli J, Chowdari N, Kaspady M, Samikannu R, Kuppusamy P, Saravanakumar P, Arunachalam PN, Deshpande S, Rangan V, Rampulla R, Mathur A, Vite GD, Gangwar S. Poudel YB, et al. Among authors: kuppusamy p. Bioorg Med Chem Lett. 2020 Jan 1;30(1):126782. doi: 10.1016/j.bmcl.2019.126782. Epub 2019 Nov 9. Bioorg Med Chem Lett. 2020. PMID: 31767265
Mass spectrometric-based investigation of differentially protected azatryptophan derivatives using Orbitrap mass spectrometry: Differentiation of positional isomers under protonation and alkali-cationization conditions.
Gajjela R, Kandula RR, Kuppusamy P, Nimje RY, Gupta A, Bagadi M, Mathur A. Gajjela R, et al. Among authors: kuppusamy p. Rapid Commun Mass Spectrom. 2022 Mar 15;36(5):e9239. doi: 10.1002/rcm.9239. Rapid Commun Mass Spectrom. 2022. PMID: 34904316
Synthesis of Differentially Protected Azatryptophan Analogs via Pd2(dba)3/XPhos Catalyzed Negishi Coupling of N-Ts Azaindole Halides with Zinc Derivative from Fmoc-Protected tert-Butyl (R)-2-Amino-3-iodopropanoate.
Nimje RY, Vytla D, Kuppusamy P, Velayuthaperumal R, Jarugu LB, Reddy CA, Chikkananjaiah NK, Rampulla RA, Cavallaro CL, Li J, Mathur A, Gupta A, Roy A. Nimje RY, et al. Among authors: kuppusamy p. J Org Chem. 2020 Sep 4;85(17):11519-11530. doi: 10.1021/acs.joc.0c00973. Epub 2020 Aug 25. J Org Chem. 2020. PMID: 32786620
Surface dielectric resonator for in vivo EPR measurements.
Petryakov SV, Kmiec MM, Ubert CS, Kassey VB, Schaner PE, Kuppusamy P. Petryakov SV, et al. Among authors: kuppusamy p. J Magn Reson. 2024 May;362:107690. doi: 10.1016/j.jmr.2024.107690. Epub 2024 Apr 25. J Magn Reson. 2024. PMID: 38692250
398 results