Izaurralde E - Search Results

1

Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation.

Peter D, Weber R, Köne C, Chung MY, Ebertsch L, Truffault V, Weichenrieder O, Igreja C, Izaurralde E. Peter D, et al. Among authors: izaurralde e. Genes Dev. 2015 Sep 1;29(17):1835-49. doi: 10.1101/gad.269068.115. Epub 2015 Aug 20. Genes Dev. 2015. PMID: 26294658 Free PMC article.

2

CUP promotes deadenylation and inhibits decapping of mRNA targets.

Igreja C, Izaurralde E. Igreja C, et al. Among authors: izaurralde e. Genes Dev. 2011 Sep 15;25(18):1955-67. doi: 10.1101/gad.17136311. Genes Dev. 2011. PMID: 21937713 Free PMC article.

3

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay.

Jonas S, Weichenrieder O, Izaurralde E. Jonas S, et al. Among authors: izaurralde e. Genes Dev. 2013 Jan 15;27(2):211-25. doi: 10.1101/gad.206672.112. Genes Dev. 2013. PMID: 23348841 Free PMC article.

4

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.

Bhandari D, Raisch T, Weichenrieder O, Jonas S, Izaurralde E. Bhandari D, et al. Among authors: izaurralde e. Genes Dev. 2014 Apr 15;28(8):888-901. doi: 10.1101/gad.237289.113. Genes Dev. 2014. PMID: 24736845 Free PMC article.

5

4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation.

Igreja C, Peter D, Weiler C, Izaurralde E. Igreja C, et al. Among authors: izaurralde e. Nat Commun. 2014 Sep 2;5:4790. doi: 10.1038/ncomms5790. Nat Commun. 2014. PMID: 25179781 Free PMC article.

6

Molecular architecture of 4E-BP translational inhibitors bound to eIF4E.

Peter D, Igreja C, Weber R, Wohlbold L, Weiler C, Ebertsch L, Weichenrieder O, Izaurralde E. Peter D, et al. Among authors: izaurralde e. Mol Cell. 2015 Mar 19;57(6):1074-1087. doi: 10.1016/j.molcel.2015.01.017. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702871 Free article.

7

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.

Keskeny C, Raisch T, Sgromo A, Igreja C, Bhandari D, Weichenrieder O, Izaurralde E. Keskeny C, et al. Among authors: izaurralde e. Genes Dev. 2019 Feb 1;33(3-4):236-252. doi: 10.1101/gad.320952.118. Epub 2019 Jan 28. Genes Dev. 2019. PMID: 30692204 Free PMC article.

8

The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.

Grüner S, Peter D, Weber R, Wohlbold L, Chung MY, Weichenrieder O, Valkov E, Igreja C, Izaurralde E. Grüner S, et al. Among authors: izaurralde e. Mol Cell. 2016 Nov 3;64(3):467-479. doi: 10.1016/j.molcel.2016.09.020. Epub 2016 Oct 20. Mol Cell. 2016. PMID: 27773676 Free article.

9

GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.

Peter D, Weber R, Sandmeir F, Wohlbold L, Helms S, Bawankar P, Valkov E, Igreja C, Izaurralde E. Peter D, et al. Among authors: izaurralde e. Genes Dev. 2017 Jun 1;31(11):1147-1161. doi: 10.1101/gad.299420.117. Epub 2017 Jul 11. Genes Dev. 2017. PMID: 28698298 Free PMC article.

10

Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.

Grüner S, Weber R, Peter D, Chung MY, Igreja C, Valkov E, Izaurralde E. Grüner S, et al. Among authors: izaurralde e. Nucleic Acids Res. 2018 Jul 27;46(13):6893-6908. doi: 10.1093/nar/gky542. Nucleic Acids Res. 2018. PMID: 30053226 Free PMC article.

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