Näsvall J - Search Results

1

Two-step Ligand Binding in a (βα)8 Barrel Enzyme: SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA.

Söderholm A, Guo X, Newton MS, Evans GB, Näsvall J, Patrick WM, Selmer M. Söderholm A, et al. Among authors: nasvall j. J Biol Chem. 2015 Oct 9;290(41):24657-68. doi: 10.1074/jbc.M115.678086. Epub 2015 Aug 20. J Biol Chem. 2015. PMID: 26294764 Free PMC article.

2

Structural and functional innovations in the real-time evolution of new (βα)₈ barrel enzymes.

Newton MS, Guo X, Söderholm A, Näsvall J, Lundström P, Andersson DI, Selmer M, Patrick WM. Newton MS, et al. Among authors: nasvall j. Proc Natl Acad Sci U S A. 2017 May 2;114(18):4727-4732. doi: 10.1073/pnas.1618552114. Epub 2017 Apr 17. Proc Natl Acad Sci U S A. 2017. PMID: 28416687 Free PMC article.

3

Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase from Salmonella enterica.

Stern AL, Van der Verren SE, Kanchugal P S, Näsvall J, Gutiérrez-de-Terán H, Selmer M. Stern AL, et al. Among authors: nasvall j. J Biol Chem. 2018 Jul 20;293(29):11481-11490. doi: 10.1074/jbc.RA118.003989. Epub 2018 Jun 5. J Biol Chem. 2018. PMID: 29871922 Free PMC article.

4

Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase.

Chen Y, Näsvall J, Wu S, Andersson DI, Selmer M. Chen Y, et al. Among authors: nasvall j. Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2267-77. doi: 10.1107/S1399004715016429. Epub 2015 Oct 31. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26527143 Free PMC article.

5

Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA.

Lundin E, Tang PC, Guy L, Näsvall J, Andersson DI. Lundin E, et al. Among authors: nasvall j. Mol Biol Evol. 2018 Mar 1;35(3):704-718. doi: 10.1093/molbev/msx325. Mol Biol Evol. 2018. PMID: 29294020 Free PMC article.

6

Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence.

Lundin E, Näsvall J, Andersson DI. Lundin E, et al. Among authors: nasvall j. Front Microbiol. 2020 Oct 14;11:588235. doi: 10.3389/fmicb.2020.588235. eCollection 2020. Front Microbiol. 2020. PMID: 33154742 Free PMC article.

7

Real-time evolution of new genes by innovation, amplification, and divergence.

Näsvall J, Sun L, Roth JR, Andersson DI. Näsvall J, et al. Science. 2012 Oct 19;338(6105):384-7. doi: 10.1126/science.1226521. Science. 2012. PMID: 23087246 Free PMC article.

8

Selection for novel metabolic capabilities in Salmonella enterica.

Warsi O, Lundin E, Lustig U, Näsvall J, Andersson DI. Warsi O, et al. Among authors: nasvall j. Evolution. 2019 May;73(5):990-1000. doi: 10.1111/evo.13713. Epub 2019 Mar 22. Evolution. 2019. PMID: 30848832 Free PMC article.

9

Activation of cryptic aminoglycoside resistance in Salmonella enterica.

Koskiniemi S, Pränting M, Gullberg E, Näsvall J, Andersson DI. Koskiniemi S, et al. Among authors: nasvall j. Mol Microbiol. 2011 Jun;80(6):1464-78. doi: 10.1111/j.1365-2958.2011.07657.x. Epub 2011 Apr 20. Mol Microbiol. 2011. PMID: 21507083 Free article.

10

Compensating the Fitness Costs of Synonymous Mutations.

Knöppel A, Näsvall J, Andersson DI. Knöppel A, et al. Among authors: nasvall j. Mol Biol Evol. 2016 Jun;33(6):1461-77. doi: 10.1093/molbev/msw028. Epub 2016 Feb 16. Mol Biol Evol. 2016. PMID: 26882986 Free PMC article.

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