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The nociceptin/orphanin FQ receptor partial agonist sunobinop promotes non-REM sleep in rodents and patients with insomnia.
Whiteside GT, Kyle DJ, Kapil RP, Cipriano A, He E, Zhou M, Shet MS, Hummel M, Knappenberger T, Fukumura K, Matsuo Y, Uehira M, Hiroyama S, Takai N, Willsie SK, Harris SC. Whiteside GT, et al. Among authors: kyle dj. J Clin Invest. 2024 Jan 2;134(1):e171172. doi: 10.1172/JCI171172. J Clin Invest. 2024. PMID: 37883189 Free PMC article.
Antibiotic exposure among young infants suffering from diarrhoea in Bangladesh.
Islam MR, Nuzhat S, Fahim SM, Palit P, Flannery RL, Kyle DJ, Mahfuz M, Islam MM, Sarker SA, Ahmed T. Islam MR, et al. Among authors: kyle dj. J Paediatr Child Health. 2021 Mar;57(3):395-402. doi: 10.1111/jpc.15233. Epub 2020 Oct 27. J Paediatr Child Health. 2021. PMID: 33107165 Free PMC article.
Hyperthermia induced by transient receptor potential vanilloid-1 (TRPV1) antagonists in human clinical trials: Insights from mathematical modeling and meta-analysis.
Garami A, Shimansky YP, Rumbus Z, Vizin RCL, Farkas N, Hegyi J, Szakacs Z, Solymar M, Csenkey A, Chiche DA, Kapil R, Kyle DJ, Van Horn WD, Hegyi P, Romanovsky AA. Garami A, et al. Among authors: kyle dj. Pharmacol Ther. 2020 Apr;208:107474. doi: 10.1016/j.pharmthera.2020.107474. Epub 2020 Jan 9. Pharmacol Ther. 2020. PMID: 31926897 Free article. Review.
Dibenzazepines and dibenzoxazepines as sodium channel blockers.
Lynch SM, Tafesse L, Carlin K, Ghatak P, Kyle DJ. Lynch SM, et al. Among authors: kyle dj. Bioorg Med Chem Lett. 2015 Jan 1;25(1):43-7. doi: 10.1016/j.bmcl.2014.11.025. Epub 2014 Nov 14. Bioorg Med Chem Lett. 2015. PMID: 25466191
N-Aryl azacycles as novel sodium channel blockers.
Lynch SM, Tafesse L, Carlin K, Ghatak P, Shao B, Abdelhamid H, Kyle DJ. Lynch SM, et al. Among authors: kyle dj. Bioorg Med Chem Lett. 2015 Jan 1;25(1):48-52. doi: 10.1016/j.bmcl.2014.11.023. Epub 2014 Nov 14. Bioorg Med Chem Lett. 2015. PMID: 25435147
101 results