Freire E - Search Results

1

Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.

Xu Q, Ensign LM, Boylan NJ, Schön A, Gong X, Yang JC, Lamb NW, Cai S, Yu T, Freire E, Hanes J. Xu Q, et al. Among authors: freire e. ACS Nano. 2015 Sep 22;9(9):9217-27. doi: 10.1021/acsnano.5b03876. Epub 2015 Aug 31. ACS Nano. 2015. PMID: 26301576 Free PMC article.

2

Thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside GM1.

Schön A, Freire E. Schön A, et al. Among authors: freire e. Biochemistry. 1989 Jun 13;28(12):5019-24. doi: 10.1021/bi00438a017. Biochemistry. 1989. PMID: 2765522

Previously, we have shown that the association of cholera toxin to ganglioside GM1 enhances the cooperative interactions between subunits in the B-subunit pentamer [Goins, B., & Freire, E. (1988) Biochemistry 27, 2046-2052]. New experiments presented in this pap …

Previously, we have shown that the association of cholera toxin to ganglioside GM1 enhances the cooperative interactions between subunits in …

3

The binding of HIV-1 protease inhibitors to human serum proteins.

Schön A, del Mar Ingaramo M, Freire E. Schön A, et al. Among authors: freire e. Biophys Chem. 2003 Sep;105(2-3):221-30. doi: 10.1016/s0301-4622(03)00071-1. Biophys Chem. 2003. PMID: 14499894

4

Multidrug resistance to HIV-1 protease inhibition requires cooperative coupling between distal mutations.

Ohtaka H, Schön A, Freire E. Ohtaka H, et al. Among authors: freire e. Biochemistry. 2003 Nov 25;42(46):13659-66. doi: 10.1021/bi0350405. Biochemistry. 2003. PMID: 14622012

5

Structural and thermodynamic basis of resistance to HIV-1 protease inhibition: implications for inhibitor design.

Velazquez-Campoy A, Muzammil S, Ohtaka H, Schön A, Vega S, Freire E. Velazquez-Campoy A, et al. Among authors: freire e. Curr Drug Targets Infect Disord. 2003 Dec;3(4):311-28. doi: 10.2174/1568005033481051. Curr Drug Targets Infect Disord. 2003. PMID: 14754432 Review.

6

Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm.

Leavitt SA, SchOn A, Klein JC, Manjappara U, Chaiken IM, Freire E. Leavitt SA, et al. Among authors: freire e. Curr Protein Pept Sci. 2004 Feb;5(1):1-8. doi: 10.2174/1389203043486955. Curr Protein Pept Sci. 2004. PMID: 14965316 Review.

7

Thermodynamic rules for the design of high affinity HIV-1 protease inhibitors with adaptability to mutations and high selectivity towards unwanted targets.

Ohtaka H, Muzammil S, Schön A, Velazquez-Campoy A, Vega S, Freire E. Ohtaka H, et al. Among authors: freire e. Int J Biochem Cell Biol. 2004 Sep;36(9):1787-99. doi: 10.1016/j.biocel.2004.02.021. Int J Biochem Cell Biol. 2004. PMID: 15183345 Review.

8

Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins.

Aguilar RC, Longhi SA, Shaw JD, Yeh LY, Kim S, Schön A, Freire E, Hsu A, McCormick WK, Watson HA, Wendland B. Aguilar RC, et al. Among authors: freire e. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4116-21. doi: 10.1073/pnas.0510513103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537494 Free PMC article.

9

Thermodynamics of binding of a low-molecular-weight CD4 mimetic to HIV-1 gp120.

Schön A, Madani N, Klein JC, Hubicki A, Ng D, Yang X, Smith AB 3rd, Sodroski J, Freire E. Schön A, et al. Among authors: freire e. Biochemistry. 2006 Sep 12;45(36):10973-80. doi: 10.1021/bi061193r. Biochemistry. 2006. PMID: 16953583 Free PMC article.

10

Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120.

Brower ET, Schön A, Klein JC, Freire E. Brower ET, et al. Among authors: freire e. Biochemistry. 2009 Feb 3;48(4):779-85. doi: 10.1021/bi8021476. Biochemistry. 2009. PMID: 19170639 Free PMC article.

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