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A computational systems biology software platform for multiscale modeling and simulation: integrating whole-body physiology, disease biology, and molecular reaction networks.
Eissing T, Kuepfer L, Becker C, Block M, Coboeken K, Gaub T, Goerlitz L, Jaeger J, Loosen R, Ludewig B, Meyer M, Niederalt C, Sevestre M, Siegmund HU, Solodenko J, Thelen K, Telle U, Weiss W, Wendl T, Willmann S, Lippert J. Eissing T, et al. Among authors: meyer m. Front Physiol. 2011 Feb 24;2:4. doi: 10.3389/fphys.2011.00004. eCollection 2011. Front Physiol. 2011. PMID: 21483730 Free PMC article.
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.
Ince I, Dallmann A, Frechen S, Coboeken K, Niederalt C, Wendl T, Block M, Meyer M, Eissing T, Burghaus R, Lippert J, Willmann S, Schlender JF. Ince I, et al. Among authors: meyer m. J Clin Pharmacol. 2021 Jun;61 Suppl 1(Suppl 1):S70-S82. doi: 10.1002/jcph.1869. J Clin Pharmacol. 2021. PMID: 34185905 Free PMC article.
Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
Frechen S, Ince I, Dallmann A, Gerisch M, Jungmann NA, Becker C, Lobmeyer M, Trujillo ME, Xu S, Burghaus R, Meyer M. Frechen S, et al. Among authors: meyer m. CPT Pharmacometrics Syst Pharmacol. 2024 Jan;13(1):79-92. doi: 10.1002/psp4.13059. Epub 2023 Oct 12. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 37794724 Free PMC article.
NT-proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure.
Schmitt W, Rühs H, Burghaus R, Diedrich C, Duwal S, Eissing T, Garmann D, Meyer M, Ploeger B, Lippert J. Schmitt W, et al. Among authors: meyer m. Clin Pharmacol Ther. 2021 Aug;110(2):498-507. doi: 10.1002/cpt.2222. Epub 2021 Mar 27. Clin Pharmacol Ther. 2021. PMID: 33630302 Free PMC article.
6,112 results