Cleary ML - Search Results

1

MLL leukemia induction by genome editing of human CD34+ hematopoietic cells.

Buechele C, Breese EH, Schneidawind D, Lin CH, Jeong J, Duque-Afonso J, Wong SH, Smith KS, Negrin RS, Porteus M, Cleary ML. Buechele C, et al. Among authors: cleary ml. Blood. 2015 Oct 1;126(14):1683-94. doi: 10.1182/blood-2015-05-646398. Epub 2015 Aug 26. Blood. 2015. PMID: 26311362 Free PMC article.

2

Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6.

Liedtke M, Ayton PM, Somervaille TC, Smith KS, Cleary ML. Liedtke M, et al. Among authors: cleary ml. Blood. 2010 Jul 8;116(1):63-70. doi: 10.1182/blood-2009-09-243386. Epub 2010 Apr 15. Blood. 2010. PMID: 20395419 Free PMC article.

3

Epigenetic roles of MLL oncoproteins are dependent on NF-κB.

Kuo HP, Wang Z, Lee DF, Iwasaki M, Duque-Afonso J, Wong SH, Lin CH, Figueroa ME, Su J, Lemischka IR, Cleary ML. Kuo HP, et al. Among authors: cleary ml. Cancer Cell. 2013 Oct 14;24(4):423-37. doi: 10.1016/j.ccr.2013.08.019. Epub 2013 Sep 19. Cancer Cell. 2013. PMID: 24054986 Free PMC article.

4

Use of Genome Engineering to Create Patient Specific MLL Translocations in Primary Human Hematopoietic Stem and Progenitor Cells.

Breese EH, Buechele C, Dawson C, Cleary ML, Porteus MH. Breese EH, et al. Among authors: cleary ml. PLoS One. 2015 Sep 9;10(9):e0136644. doi: 10.1371/journal.pone.0136644. eCollection 2015. PLoS One. 2015. PMID: 26351841 Free PMC article.

5

ASH1L Links Histone H3 Lysine 36 Dimethylation to MLL Leukemia.

Zhu L, Li Q, Wong SH, Huang M, Klein BJ, Shen J, Ikenouye L, Onishi M, Schneidawind D, Buechele C, Hansen L, Duque-Afonso J, Zhu F, Martin GM, Gozani O, Majeti R, Kutateladze TG, Cleary ML. Zhu L, et al. Among authors: cleary ml. Cancer Discov. 2016 Jul;6(7):770-83. doi: 10.1158/2159-8290.CD-16-0058. Epub 2016 May 6. Cancer Discov. 2016. PMID: 27154821 Free PMC article.

6

MLL leukemia induction by t(9;11) chromosomal translocation in human hematopoietic stem cells using genome editing.

Schneidawind C, Jeong J, Schneidawind D, Kim IS, Duque-Afonso J, Wong SHK, Iwasaki M, Breese EH, Zehnder JL, Porteus M, Cleary ML. Schneidawind C, et al. Among authors: cleary ml. Blood Adv. 2018 Apr 24;2(8):832-845. doi: 10.1182/bloodadvances.2017013748. Blood Adv. 2018. PMID: 29650777 Free PMC article.

7

High-efficiency CRISPR induction of t(9;11) chromosomal translocations and acute leukemias in human blood stem cells.

Jeong J, Jager A, Domizi P, Pavel-Dinu M, Gojenola L, Iwasaki M, Wei MC, Pan F, Zehnder JL, Porteus MH, Davis KL, Cleary ML. Jeong J, et al. Among authors: cleary ml. Blood Adv. 2019 Oct 8;3(19):2825-2835. doi: 10.1182/bloodadvances.2019000450. Blood Adv. 2019. PMID: 31582391 Free PMC article.

8

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.

Yokoyama A, Somervaille TC, Smith KS, Rozenblatt-Rosen O, Meyerson M, Cleary ML. Yokoyama A, et al. Among authors: cleary ml. Cell. 2005 Oct 21;123(2):207-18. doi: 10.1016/j.cell.2005.09.025. Cell. 2005. PMID: 16239140 Free article.

9

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

Wang Z, Smith KS, Murphy M, Piloto O, Somervaille TC, Cleary ML. Wang Z, et al. Among authors: cleary ml. Nature. 2008 Oct 30;455(7217):1205-9. doi: 10.1038/nature07284. Epub 2008 Sep 17. Nature. 2008. PMID: 18806775 Free PMC article.

10

GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis.

Wang Z, Iwasaki M, Ficara F, Lin C, Matheny C, Wong SH, Smith KS, Cleary ML. Wang Z, et al. Among authors: cleary ml. Cancer Cell. 2010 Jun 15;17(6):597-608. doi: 10.1016/j.ccr.2010.04.024. Cancer Cell. 2010. PMID: 20541704 Free PMC article.

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