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A novel small-molecule IAP antagonist, AZD5582, draws Mcl-1 down-regulation for induction of apoptosis through targeting of cIAP1 and XIAP in human pancreatic cancer.
Moon JH, Shin JS, Hong SW, Jung SA, Hwang IY, Kim JH, Choi EK, Ha SH, Kim JS, Kim KM, Hong DW, Kim D, Kim YS, Kim JE, Kim KP, Hong YS, Choi EK, Lee JS, Hattersley M, Jin DH, Kim TW. Moon JH, et al. Among authors: ha sh. Oncotarget. 2015 Sep 29;6(29):26895-908. doi: 10.18632/oncotarget.4822. Oncotarget. 2015. PMID: 26314849 Free PMC article.
Targeting β-catenin overcomes MEK inhibition resistance in colon cancer with KRAS and PIK3CA mutations.
Moon JH, Hong SW, Kim JE, Shin JS, Kim JS, Jung SA, Ha SH, Lee S, Kim J, Lee DH, Park YS, Kim DM, Park SS, Hong JK, Kim DY, Kim EH, Jung J, Kim MJ, Kim SM, Deming DA, Kim K, Kim TW, Jin DH. Moon JH, et al. Among authors: ha sh. Br J Cancer. 2019 Apr;120(9):941-951. doi: 10.1038/s41416-019-0434-5. Epub 2019 Apr 4. Br J Cancer. 2019. PMID: 30944457 Free PMC article.
347 results