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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S. Patel A, et al. Among authors: franzmann tm. Cell. 2015 Aug 27;162(5):1066-77. doi: 10.1016/j.cell.2015.07.047. Cell. 2015. PMID: 26317470 Free article.
Phase separation of a yeast prion protein promotes cellular fitness.
Franzmann TM, Jahnel M, Pozniakovsky A, Mahamid J, Holehouse AS, Nüske E, Richter D, Baumeister W, Grill SW, Pappu RV, Hyman AA, Alberti S. Franzmann TM, et al. Science. 2018 Jan 5;359(6371):eaao5654. doi: 10.1126/science.aao5654. Science. 2018. PMID: 29301985
RNA buffers the phase separation behavior of prion-like RNA binding proteins.
Maharana S, Wang J, Papadopoulos DK, Richter D, Pozniakovsky A, Poser I, Bickle M, Rizk S, Guillén-Boixet J, Franzmann TM, Jahnel M, Marrone L, Chang YT, Sterneckert J, Tomancak P, Hyman AA, Alberti S. Maharana S, et al. Among authors: franzmann tm. Science. 2018 May 25;360(6391):918-921. doi: 10.1126/science.aar7366. Epub 2018 Apr 12. Science. 2018. PMID: 29650702 Free PMC article.
A User's Guide for Phase Separation Assays with Purified Proteins.
Alberti S, Saha S, Woodruff JB, Franzmann TM, Wang J, Hyman AA. Alberti S, et al. Among authors: franzmann tm. J Mol Biol. 2018 Nov 2;430(23):4806-4820. doi: 10.1016/j.jmb.2018.06.038. Epub 2018 Jun 23. J Mol Biol. 2018. PMID: 29944854 Free PMC article.
Protein Phase Separation as a Stress Survival Strategy.
Franzmann TM, Alberti S. Franzmann TM, et al. Cold Spring Harb Perspect Biol. 2019 Jun 3;11(6):a034058. doi: 10.1101/cshperspect.a034058. Cold Spring Harb Perspect Biol. 2019. PMID: 30617047 Free PMC article. Review.
46 results