Shen B - Search Results

1

Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.

Rudolf JD, Yan X, Shen B. Rudolf JD, et al. Among authors: shen b. J Ind Microbiol Biotechnol. 2016 Mar;43(2-3):261-76. doi: 10.1007/s10295-015-1671-0. Epub 2015 Aug 29. J Ind Microbiol Biotechnol. 2016. PMID: 26318027 Free PMC article.

2

4-methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis.

Lohman JR, Shen B. Lohman JR, et al. Among authors: shen b. Methods Enzymol. 2012;516:299-319. doi: 10.1016/B978-0-12-394291-3.00007-1. Methods Enzymol. 2012. PMID: 23034235

3

Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.

Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B. Lohman JR, et al. Among authors: shen b. Mol Biosyst. 2013 Mar;9(3):478-91. doi: 10.1039/c3mb25523a. Epub 2013 Jan 29. Mol Biosyst. 2013. PMID: 23360970 Free PMC article.

4

Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes.

Xie P, Ma M, Rateb ME, Shaaban KA, Yu Z, Huang SX, Zhao LX, Zhu X, Yan Y, Peterson RM, Lohman JR, Yang D, Yin M, Rudolf JD, Jiang Y, Duan Y, Shen B. Xie P, et al. Among authors: shen b. J Nat Prod. 2014 Feb 28;77(2):377-87. doi: 10.1021/np401063s. Epub 2014 Jan 31. J Nat Prod. 2014. PMID: 24484381 Free PMC article.

5

Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.

Peterson RM, Huang T, Rudolf JD, Smanski MJ, Shen B. Peterson RM, et al. Among authors: shen b. Chem Biol. 2014 Mar 20;21(3):389-397. doi: 10.1016/j.chembiol.2014.01.005. Epub 2014 Feb 20. Chem Biol. 2014. PMID: 24560608 Free PMC article.

6

Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β-D-hydroxyacyl intermediates in enediyne core biosynthesis.

Ge HM, Huang T, Rudolf JD, Lohman JR, Huang SX, Guo X, Shen B. Ge HM, et al. Among authors: shen b. Org Lett. 2014 Aug 1;16(15):3958-61. doi: 10.1021/ol501767v. Epub 2014 Jul 14. Org Lett. 2014. PMID: 25019332 Free PMC article.

7

Strain prioritization for natural product discovery by a high-throughput real-time PCR method.

Hindra, Huang T, Yang D, Rudolf JD, Xie P, Xie G, Teng Q, Lohman JR, Zhu X, Huang Y, Zhao LX, Jiang Y, Duan Y, Shen B. Hindra, et al. Among authors: shen b. J Nat Prod. 2014 Oct 24;77(10):2296-303. doi: 10.1021/np5006168. Epub 2014 Sep 19. J Nat Prod. 2014. PMID: 25238028 Free PMC article.

8

BlmB and TlmB provide resistance to the bleomycin family of antitumor antibiotics by N-acetylating metal-free bleomycin, tallysomycin, phleomycin, and zorbamycin.

Coughlin JM, Rudolf JD, Wendt-Pienkowski E, Wang L, Unsin C, Galm U, Yang D, Tao M, Shen B. Coughlin JM, et al. Among authors: shen b. Biochemistry. 2014 Nov 11;53(44):6901-9. doi: 10.1021/bi501121e. Epub 2014 Oct 23. Biochemistry. 2014. PMID: 25299801 Free PMC article.

9

Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.

Shen B, Hindra, Yan X, Huang T, Ge H, Yang D, Teng Q, Rudolf JD, Lohman JR. Shen B, et al. Bioorg Med Chem Lett. 2015 Jan 1;25(1):9-15. doi: 10.1016/j.bmcl.2014.11.019. Epub 2014 Nov 14. Bioorg Med Chem Lett. 2015. PMID: 25434000 Free PMC article. Review.

10

A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase.

Rudolf JD, Dong LB, Huang T, Shen B. Rudolf JD, et al. Among authors: shen b. Mol Biosyst. 2015 Oct;11(10):2717-26. doi: 10.1039/c5mb00303b. Mol Biosyst. 2015. PMID: 26055255 Free PMC article.

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