Zhang Z - Search Results

1

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.

Dahlin JL, Nissink JWM, Francis S, Strasser JM, John K, Zhang Z, Walters MA. Dahlin JL, et al. Among authors: zhang z. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4740-4752. doi: 10.1016/j.bmcl.2015.08.020. Epub 2015 Aug 10. Bioorg Med Chem Lett. 2015. PMID: 26318992 Free PMC article.

2

A cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylation.

Dahlin JL, Sinville R, Solberg J, Zhou H, Han J, Francis S, Strasser JM, John K, Hook DJ, Walters MA, Zhang Z. Dahlin JL, et al. Among authors: zhang z. PLoS One. 2013 Nov 18;8(11):e78877. doi: 10.1371/journal.pone.0078877. eCollection 2013. PLoS One. 2013. PMID: 24260132 Free PMC article.

3

PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.

Dahlin JL, Nissink JW, Strasser JM, Francis S, Higgins L, Zhou H, Zhang Z, Walters MA. Dahlin JL, et al. Among authors: zhang z. J Med Chem. 2015 Mar 12;58(5):2091-113. doi: 10.1021/jm5019093. Epub 2015 Feb 21. J Med Chem. 2015. PMID: 25634295 Free PMC article.

4

Pneumocystis jirovecii Rtt109, a novel drug target for Pneumocystis pneumonia in immunosuppressed humans.

Dahlin JL, Kottom T, Han J, Zhou H, Walters MA, Zhang Z, Limper AH. Dahlin JL, et al. Among authors: zhang z. Antimicrob Agents Chemother. 2014 Jul;58(7):3650-9. doi: 10.1128/AAC.02637-14. Epub 2014 Apr 14. Antimicrob Agents Chemother. 2014. PMID: 24733475 Free PMC article.

5

Histone-modifying enzymes, histone modifications and histone chaperones in nucleosome assembly: Lessons learned from Rtt109 histone acetyltransferases.

Dahlin JL, Chen X, Walters MA, Zhang Z. Dahlin JL, et al. Among authors: zhang z. Crit Rev Biochem Mol Biol. 2015 Jan-Feb;50(1):31-53. doi: 10.3109/10409238.2014.978975. Epub 2014 Nov 3. Crit Rev Biochem Mol Biol. 2015. PMID: 25365782 Free PMC article. Review.

6

Structure and histone binding properties of the Vps75-Rtt109 chaperone-lysine acetyltransferase complex.

Su D, Hu Q, Zhou H, Thompson JR, Xu RM, Zhang Z, Mer G. Su D, et al. Among authors: zhang z. J Biol Chem. 2011 May 6;286(18):15625-9. doi: 10.1074/jbc.C111.220715. Epub 2011 Mar 22. J Biol Chem. 2011. PMID: 21454705 Free PMC article.

7

Histone chaperone Rtt106 promotes nucleosome formation using (H3-H4)2 tetramers.

Fazly A, Li Q, Hu Q, Mer G, Horazdovsky B, Zhang Z. Fazly A, et al. Among authors: zhang z. J Biol Chem. 2012 Mar 30;287(14):10753-60. doi: 10.1074/jbc.M112.347450. Epub 2012 Feb 15. J Biol Chem. 2012. PMID: 22337870 Free PMC article.

8

The Rtt109-Vps75 histone acetyltransferase complex acetylates non-nucleosomal histone H3.

Han J, Zhou H, Li Z, Xu RM, Zhang Z. Han J, et al. Among authors: zhang z. J Biol Chem. 2007 May 11;282(19):14158-64. doi: 10.1074/jbc.M700611200. Epub 2007 Mar 16. J Biol Chem. 2007. PMID: 17369253 Free article.

9

Roles for Gcn5 in promoting nucleosome assembly and maintaining genome integrity.

Burgess RJ, Zhang Z. Burgess RJ, et al. Among authors: zhang z. Cell Cycle. 2010 Aug 1;9(15):2979-85. doi: 10.4161/cc.9.15.12498. Epub 2010 Aug 23. Cell Cycle. 2010. PMID: 20699646 Free PMC article.

10

Pneumocystis carinii expresses an active Rtt109 histone acetyltransferase.

Kottom TJ, Han J, Zhang Z, Limper AH. Kottom TJ, et al. Among authors: zhang z. Am J Respir Cell Mol Biol. 2011 Jun;44(6):768-76. doi: 10.1165/rcmb.2009-0443OC. Epub 2010 Jul 23. Am J Respir Cell Mol Biol. 2011. PMID: 20656950 Free PMC article.

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