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Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
Herbert AP, Deakin JA, Schmidt CQ, Blaum BS, Egan C, Ferreira VP, Pangburn MK, Lyon M, Uhrín D, Barlow PN. Herbert AP, et al. Among authors: schmidt cq. J Biol Chem. 2007 Jun 29;282(26):18960-8. doi: 10.1074/jbc.M609636200. Epub 2007 Mar 13. J Biol Chem. 2007. PMID: 17360715 Free article.
Using mutagenesis and structural biology to map the binding site for the Plasmodium falciparum merozoite protein PfRh4 on the human immune adherence receptor.
Park HJ, Guariento M, Maciejewski M, Hauhart R, Tham WH, Cowman AF, Schmidt CQ, Mertens HD, Liszewski MK, Hourcade DE, Barlow PN, Atkinson JP. Park HJ, et al. Among authors: schmidt cq. J Biol Chem. 2014 Jan 3;289(1):450-63. doi: 10.1074/jbc.M113.520346. Epub 2013 Nov 8. J Biol Chem. 2014. PMID: 24214979 Free PMC article.
Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation.
Harder MJ, Anliker M, Höchsmann B, Simmet T, Huber-Lang M, Schrezenmeier H, Ricklin D, Lambris JD, Barlow PN, Schmidt CQ. Harder MJ, et al. Among authors: schmidt cq. J Immunol. 2016 Jan 15;196(2):866-76. doi: 10.4049/jimmunol.1501919. Epub 2015 Dec 7. J Immunol. 2016. PMID: 26643478 Free PMC article.
74 results