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Page 1
NDRG1 links p53 with proliferation-mediated centrosome homeostasis and genome stability.
Croessmann S, Wong HY, Zabransky DJ, Chu D, Mendonca J, Sharma A, Mohseni M, Rosen DM, Scharpf RB, Cidado J, Cochran RL, Parsons HA, Dalton WB, Erlanger B, Button B, Cravero K, Kyker-Snowman K, Beaver JA, Kachhap S, Hurley PJ, Lauring J, Park BH. Croessmann S, et al. Among authors: cochran rl. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11583-8. doi: 10.1073/pnas.1503683112. Epub 2015 Aug 31. Proc Natl Acad Sci U S A. 2015. PMID: 26324937 Free PMC article.
MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.
Mohseni M, Cidado J, Croessmann S, Cravero K, Cimino-Mathews A, Wong HY, Scharpf R, Zabransky DJ, Abukhdeir AM, Garay JP, Wang GM, Beaver JA, Cochran RL, Blair BG, Rosen DM, Erlanger B, Argani P, Hurley PJ, Lauring J, Park BH. Mohseni M, et al. Among authors: cochran rl. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17606-11. doi: 10.1073/pnas.1408650111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422431 Free PMC article.
Functional isogenic modeling of BRCA1 alleles reveals distinct carrier phenotypes.
Cochran RL, Cidado J, Kim M, Zabransky DJ, Croessmann S, Chu D, Wong HY, Beaver JA, Cravero K, Erlanger B, Parsons H, Heaphy CM, Meeker AK, Lauring J, Park BH. Cochran RL, et al. Oncotarget. 2015 Sep 22;6(28):25240-51. doi: 10.18632/oncotarget.4595. Oncotarget. 2015. PMID: 26246475 Free PMC article.
HER2 missense mutations have distinct effects on oncogenic signaling and migration.
Zabransky DJ, Yankaskas CL, Cochran RL, Wong HY, Croessmann S, Chu D, Kavuri SM, Red Brewer M, Rosen DM, Dalton WB, Cimino-Mathews A, Cravero K, Button B, Kyker-Snowman K, Cidado J, Erlanger B, Parsons HA, Manto KM, Bose R, Lauring J, Arteaga CL, Konstantopoulos K, Park BH. Zabransky DJ, et al. Among authors: cochran rl. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6205-14. doi: 10.1073/pnas.1516853112. Epub 2015 Oct 27. Proc Natl Acad Sci U S A. 2015. PMID: 26508629 Free PMC article.
Ki-67 is required for maintenance of cancer stem cells but not cell proliferation.
Cidado J, Wong HY, Rosen DM, Cimino-Mathews A, Garay JP, Fessler AG, Rasheed ZA, Hicks J, Cochran RL, Croessmann S, Zabransky DJ, Mohseni M, Beaver JA, Chu D, Cravero K, Christenson ES, Medford A, Mattox A, De Marzo AM, Argani P, Chawla A, Hurley PJ, Lauring J, Park BH. Cidado J, et al. Among authors: cochran rl. Oncotarget. 2016 Feb 2;7(5):6281-93. doi: 10.18632/oncotarget.7057. Oncotarget. 2016. PMID: 26823390 Free PMC article.
PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.
Croessmann S, Wong HY, Zabransky DJ, Chu D, Rosen DM, Cidado J, Cochran RL, Dalton WB, Erlanger B, Cravero K, Button B, Kyker-Snowman K, Hurley PJ, Lauring J, Park BH. Croessmann S, et al. Among authors: cochran rl. Breast Cancer Res Treat. 2017 Apr;162(3):451-464. doi: 10.1007/s10549-017-4147-2. Epub 2017 Feb 11. Breast Cancer Res Treat. 2017. PMID: 28190247 Free PMC article.
Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells.
Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, Karnan S, Ota A, Wong HY, Konishi Y, Karakas B, Tahir K, Abukhdeir AM, Gustin JP, Cidado J, Wang GM, Cosgrove D, Cochran R, Jelovac D, Higgins MJ, Arena S, Hawkins L, Lauring J, Gross AL, Heaphy CM, Hosokawa Y, Gabrielson E, Meeker AK, Visvanathan K, Argani P, Bachman KE, Park BH. Konishi H, et al. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17773-8. doi: 10.1073/pnas.1110969108. Epub 2011 Oct 10. Proc Natl Acad Sci U S A. 2011. PMID: 21987798 Free PMC article.
Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.
Wang GM, Wong HY, Konishi H, Blair BG, Abukhdeir AM, Gustin JP, Rosen DM, Denmeade SR, Rasheed Z, Matsui W, Garay JP, Mohseni M, Higgins MJ, Cidado J, Jelovac D, Croessmann S, Cochran RL, Karnan S, Konishi Y, Ota A, Hosokawa Y, Argani P, Lauring J, Park BH. Wang GM, et al. Among authors: cochran rl. Cancer Res. 2013 Jun 1;73(11):3248-61. doi: 10.1158/0008-5472.CAN-12-1578. Epub 2013 Apr 11. Cancer Res. 2013. PMID: 23580570 Free PMC article.
59 results