De Luca A - Search Results

1

Nitrobenzoxadiazole-based GSTP1-1 inhibitors containing the full peptidyl moiety of (pseudo)glutathione.

Luisi G, Mollica A, Carradori S, Lenoci A, De Luca A, Caccuri AM. Luisi G, et al. Among authors: de luca a. J Enzyme Inhib Med Chem. 2016 Dec;31(6):924-30. doi: 10.3109/14756366.2015.1070845. Epub 2015 Sep 2. J Enzyme Inhib Med Chem. 2016. PMID: 26329912 Free article.

2

New insights into the mechanism of JNK1 inhibition by glutathione transferase P1-1.

De Luca A, Federici L, De Canio M, Stella L, Caccuri AM. De Luca A, et al. Among authors: de canio m. Biochemistry. 2012 Sep 18;51(37):7304-12. doi: 10.1021/bi300559m. Epub 2012 Sep 5. Biochemistry. 2012. PMID: 22920299

3

Glutathione S-transferase P1-1 as a target for mesothelioma treatment.

De Luca A, Pellizzari Tregno F, Sau A, Pastore A, Palumbo C, Alama A, Cicconi R, Federici G, Caccuri AM. De Luca A, et al. Cancer Sci. 2013 Feb;104(2):223-30. doi: 10.1111/cas.12061. Epub 2012 Dec 24. Cancer Sci. 2013. PMID: 23121163 Free PMC article.

4

A new target for gold(I) compounds: glutathione-S-transferase inhibition by auranofin.

De Luca A, Hartinger CG, Dyson PJ, Lo Bello M, Casini A. De Luca A, et al. J Inorg Biochem. 2013 Feb;119:38-42. doi: 10.1016/j.jinorgbio.2012.08.006. Epub 2012 Aug 24. J Inorg Biochem. 2013. PMID: 23183361

5

The fine-tuning of TRAF2-GSTP1-1 interaction: effect of ligand binding and in situ detection of the complex.

De Luca A, Mei G, Rosato N, Nicolai E, Federici L, Palumbo C, Pastore A, Serra M, Caccuri AM. De Luca A, et al. Cell Death Dis. 2014 Jan 23;5(1):e1015. doi: 10.1038/cddis.2013.529. Cell Death Dis. 2014. PMID: 24457959 Free PMC article.

6

Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.

Rotili D, De Luca A, Tarantino D, Pezzola S, Forgione M, Morozzo Della Rocca B, Falconi M, Mai A, Caccuri AM. Rotili D, et al. Among authors: de luca a. Eur J Med Chem. 2015 Jan 7;89:156-71. doi: 10.1016/j.ejmech.2014.10.033. Epub 2014 Oct 13. Eur J Med Chem. 2015. PMID: 25462236

7

A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.

De Luca A, Rotili D, Carpanese D, Lenoci A, Calderan L, Scimeca M, Mai A, Bonanno E, Rosato A, Geroni C, Quintieri L, Caccuri AM. De Luca A, et al. Oncotarget. 2015 Feb 28;6(6):4126-43. doi: 10.18632/oncotarget.2798. Oncotarget. 2015. PMID: 25595904 Free PMC article.

8

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib.

Graziani G, Artuso S, De Luca A, Muzi A, Rotili D, Scimeca M, Atzori MG, Ceci C, Mai A, Leonetti C, Levati L, Bonanno E, Tentori L, Caccuri AM. Graziani G, et al. Among authors: de luca a. Biochem Pharmacol. 2015 May 1;95(1):16-27. doi: 10.1016/j.bcp.2015.03.004. Epub 2015 Mar 17. Biochem Pharmacol. 2015. PMID: 25795251

9

TNFR-Associated Factor-2 (TRAF2): Not Only a Trimer.

Ceccarelli A, Di Venere A, Nicolai E, De Luca A, Minicozzi V, Rosato N, Caccuri AM, Mei G. Ceccarelli A, et al. Among authors: de luca a. Biochemistry. 2015 Oct 13;54(40):6153-61. doi: 10.1021/acs.biochem.5b00674. Epub 2015 Sep 30. Biochemistry. 2015. PMID: 26390021

10

c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition.

Palumbo C, De Luca A, Rosato N, Forgione M, Rotili D, Caccuri AM. Palumbo C, et al. Among authors: de luca a. J Transl Med. 2016 Feb 4;14:37. doi: 10.1186/s12967-016-0796-x. J Transl Med. 2016. PMID: 26847645 Free PMC article.

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