Jin Q - Search Results

1

Synthesis and biological evaluation of novel 7-substituted 3-(4-phenoxyphenyl)thieno[3,2-c]pyridin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors.

Xin M, Zhao X, Huang W, Jin Q, Wu G, Wang Y, Tang F, Xiang H. Xin M, et al. Among authors: jin q. Bioorg Med Chem. 2015 Oct 1;23(19):6250-7. doi: 10.1016/j.bmc.2015.08.039. Epub 2015 Aug 28. Bioorg Med Chem. 2015. PMID: 26344595

2

Design, synthesis, and biological evaluation of novel 3-pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives as potent receptor tyrosine kinase inhibitors.

Ding L, Tang F, Huang W, Jin Q, Shen H, Wei P. Ding L, et al. Among authors: jin q. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5630-3. doi: 10.1016/j.bmcl.2013.08.037. Epub 2013 Aug 15. Bioorg Med Chem Lett. 2013. PMID: 23999040

3

Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors.

Zhao X, Xin M, Huang W, Ren Y, Jin Q, Tang F, Jiang H, Wang Y, Yang J, Mo S, Xiang H. Zhao X, et al. Among authors: jin q. Bioorg Med Chem. 2015 Jan 15;23(2):348-64. doi: 10.1016/j.bmc.2014.11.006. Epub 2014 Nov 10. Bioorg Med Chem. 2015. PMID: 25515957

4

Discovery of novel Bruton's tyrosine kinase (BTK) inhibitors bearing a pyrrolo[2,3-d]pyrimidine scaffold.

Zhao X, Huang W, Wang Y, Xin M, Jin Q, Cai J, Tang F, Zhao Y, Xiang H. Zhao X, et al. Among authors: jin q. Bioorg Med Chem. 2015 Feb 15;23(4):891-901. doi: 10.1016/j.bmc.2014.10.043. Epub 2014 Nov 6. Bioorg Med Chem. 2015. PMID: 25596757

5

Pyrrolo[2,3-b]pyridine derivatives as potent Bruton's tyrosine kinase inhibitors.

Zhao X, Huang W, Wang Y, Xin M, Jin Q, Cai J, Tang F, Zhao Y, Xiang H. Zhao X, et al. Among authors: jin q. Bioorg Med Chem. 2015 Aug 1;23(15):4344-4353. doi: 10.1016/j.bmc.2015.06.023. Epub 2015 Jun 17. Bioorg Med Chem. 2015. PMID: 26169764

6

Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton's tyrosine kinase (BTK) inhibitors.

Zhao X, Xin M, Wang Y, Huang W, Jin Q, Tang F, Wu G, Zhao Y, Xiang H. Zhao X, et al. Among authors: jin q. Bioorg Med Chem. 2015 Sep 1;23(17):6059-68. doi: 10.1016/j.bmc.2015.05.043. Epub 2015 May 31. Bioorg Med Chem. 2015. PMID: 26277759

7

Discovery of novel 4-(2-pyrimidinylamino)benzamide derivatives as highly potent and orally available hedgehog signaling pathway inhibitors.

Xin M, Zhang L, Jin Q, Tang F, Wen J, Gu L, Cheng L, Zhao Y. Xin M, et al. Among authors: jin q. Eur J Med Chem. 2016 Mar 3;110:115-25. doi: 10.1016/j.ejmech.2016.01.018. Epub 2016 Jan 20. Eur J Med Chem. 2016. PMID: 26820554

8

Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors.

Xin M, Zhang L, Wen J, Shen H, Liu Z, Zhao X, Jin Q, Wang M, Cheng L, Huang W, Tang F. Xin M, et al. Among authors: jin q. Bioorg Med Chem. 2016 Mar 1;24(5):1079-88. doi: 10.1016/j.bmc.2016.01.034. Epub 2016 Jan 19. Bioorg Med Chem. 2016. PMID: 26827136

9

Introduction of fluorine to phenyl group of 4-(2-pyrimidinylamino)benzamides leading to a series of potent hedgehog signaling pathway inhibitors.

Xin M, Zhang L, Wen J, Shen H, Zhao X, Jin Q, Tang F. Xin M, et al. Among authors: jin q. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3259-3263. doi: 10.1016/j.bmcl.2017.06.030. Epub 2017 Jun 13. Bioorg Med Chem Lett. 2017. PMID: 28642101

10

Design and synthesis of novel phthalazinone derivatives as potent poly(ADP-ribose)polymerase 1 inhibitors.

Xin M, Sun J, Huang W, Tang F, Liu Z, Jin Q, Wang J. Xin M, et al. Among authors: jin q. Future Med Chem. 2020 Oct;12(19):1691-1707. doi: 10.4155/fmc-2020-0009. Epub 2020 Oct 5. Future Med Chem. 2020. PMID: 33012191

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