Yoshii K - Search Results

1

Physiologically-Based Pharmacokinetic and Pharmacodynamic Modeling for the Inhibition of Acetylcholinesterase by Acotiamide, A Novel Gastroprokinetic Agent for the Treatment of Functional Dyspepsia, in Rat Stomach.

Yoshii K, Iikura M, Hirayama M, Toda R, Kawabata Y. Yoshii K, et al. Pharm Res. 2016 Feb;33(2):292-300. doi: 10.1007/s11095-015-1787-y. Epub 2015 Sep 9. Pharm Res. 2016. PMID: 26350104 Free PMC article.

2

Mechanism for distribution of acotiamide, a novel gastroprokinetic agent for the treatment of functional dyspepsia, in rat stomach.

Yoshii K, Hirayama M, Nakamura T, Toda R, Hasegawa J, Takei M, Mera Y, Kawabata Y. Yoshii K, et al. J Pharm Sci. 2011 Nov;100(11):4965-73. doi: 10.1002/jps.22649. Epub 2011 May 31. J Pharm Sci. 2011. PMID: 21630282

3

Acotiamide hydrochloride (Z-338) enhances gastric motility and emptying by inhibiting acetylcholinesterase activity in rats.

Kawachi M, Matsunaga Y, Tanaka T, Hori Y, Ito K, Nagahama K, Ozaki T, Inoue N, Toda R, Yoshii K, Hirayama M, Kawabata Y, Takei M. Kawachi M, et al. Among authors: yoshii k. Eur J Pharmacol. 2011 Sep;666(1-3):218-25. doi: 10.1016/j.ejphar.2011.05.049. Epub 2011 Jun 1. Eur J Pharmacol. 2011. PMID: 21651906

4

Distribution of acotiamide, an orally active acetylcholinesterase inhibitor, into the myenteric plexus of rat and dog stomachs.

Yoshii K, Yamaguchi T, Hirayama M, Toda R, Kinomoto T, Kawabata Y, Chiba K. Yoshii K, et al. Life Sci. 2016 Jan 15;145:93-7. doi: 10.1016/j.lfs.2015.12.020. Epub 2015 Dec 10. Life Sci. 2016. PMID: 26682939 Free article.

5

Identification of the Uptake Transporter Responsible for Distribution of Acotiamide into Stomach Tissue.

Hirayama M, Hoshino Y, Yoshii K, Toda R, Kawabata Y, Nakanishi T, Tamai I. Hirayama M, et al. Among authors: yoshii k. Mol Pharm. 2020 Apr 6;17(4):1071-1078. doi: 10.1021/acs.molpharmaceut.9b00894. Epub 2020 Mar 10. Mol Pharm. 2020. PMID: 32105080

6

Pharmacological evaluation of analgesic effects of the cholecystokinin2 receptor antagonist Z-360 in mouse models of formalin- and cancer-induced pain.

Yoshinaga K, Horii T, Hamano H, Eta R, Ozaki T, Orikawa Y, Yoshii K, Kawabata Y, Hori Y, Seto K, Takei M, Kuraishi Y. Yoshinaga K, et al. Among authors: yoshii k. Biol Pharm Bull. 2010;33(2):244-8. doi: 10.1248/bpb.33.244. Biol Pharm Bull. 2010. PMID: 20118547 Free article.

7

Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride.

Matsunaga Y, Tanaka T, Yoshinaga K, Ueki S, Hori Y, Eta R, Kawabata Y, Yoshii K, Yoshida K, Matsumura T, Furuta S, Takei M, Tack J, Itoh Z. Matsunaga Y, et al. Among authors: yoshii k. J Pharmacol Exp Ther. 2011 Mar;336(3):791-800. doi: 10.1124/jpet.110.174847. Epub 2010 Dec 1. J Pharmacol Exp Ther. 2011. PMID: 21123674

8

Concentration dependence of 5-aminosalicylic acid pharmacological actions in intestinal mucosa after oral administration of a pH-dependent formulation.

Hirayama M, Toda R, Ozaki T, Hasegawa J, Nakamura T, Naraki Y, Haraguchi Y, Hori Y, Tanaka T, Takei M, Mera Y, Yoshii K, Kawabata Y. Hirayama M, et al. Among authors: yoshii k. Mol Pharm. 2011 Aug 1;8(4):1083-9. doi: 10.1021/mp200088z. Epub 2011 May 19. Mol Pharm. 2011. PMID: 21553927

9

Mass balance and metabolism of Z-215, a novel proton pump inhibitor, in healthy volunteers.

Toda R, Miyagawa T, Masuda Y, Hoshino Y, Yoshii K, Hirayama M, Shibuya M, Kawabata Y. Toda R, et al. Among authors: yoshii k. Xenobiotica. 2018 Oct;48(10):1006-1020. doi: 10.1080/00498254.2017.1390625. Epub 2017 Nov 2. Xenobiotica. 2018. PMID: 29092680 Clinical Trial.

10

Pharmacokinetics and Pharmacodynamics of Azeloprazole Sodium, a Novel Proton Pump Inhibitor, in Healthy Japanese Volunteers.

Toda R, Shiramoto M, Komai E, Yoshii K, Hirayama M, Kawabata Y. Toda R, et al. Among authors: yoshii k. J Clin Pharmacol. 2018 Apr;58(4):425-433. doi: 10.1002/jcph.1038. Epub 2017 Nov 28. J Clin Pharmacol. 2018. PMID: 29193126 Clinical Trial.

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