Yu H - Search Results

1

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system.

Wang X, Yu H, Lei A, Zhou J, Zeng W, Zhu H, Dong Z, Niu Y, Shi B, Cai B, Liu J, Huang S, Yan H, Zhao X, Zhou G, He X, Chen X, Yang Y, Jiang Y, Shi L, Tian X, Wang Y, Ma B, Huang X, Qu L, Chen Y. Wang X, et al. Among authors: yu h. Sci Rep. 2015 Sep 10;5:13878. doi: 10.1038/srep13878. Sci Rep. 2015. PMID: 26354037 Free PMC article.

2

Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep.

Wang X, Niu Y, Zhou J, Yu H, Kou Q, Lei A, Zhao X, Yan H, Cai B, Shen Q, Zhou S, Zhu H, Zhou G, Niu W, Hua J, Jiang Y, Huang X, Ma B, Chen Y. Wang X, et al. Among authors: yu h. Sci Rep. 2016 Aug 26;6:32271. doi: 10.1038/srep32271. Sci Rep. 2016. PMID: 27562433 Free PMC article.

3

Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers.

Wang X, Cai B, Zhou J, Zhu H, Niu Y, Ma B, Yu H, Lei A, Yan H, Shen Q, Shi L, Zhao X, Hua J, Huang X, Qu L, Chen Y. Wang X, et al. Among authors: yu h. PLoS One. 2016 Oct 18;11(10):e0164640. doi: 10.1371/journal.pone.0164640. eCollection 2016. PLoS One. 2016. PMID: 27755602 Free PMC article.

4

Generation of gene-edited sheep with a defined Booroola fecundity gene (FecB^B) mutation in bone morphogenetic protein receptor type 1B (BMPR1B) via clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) 9.

Zhou S, Yu H, Zhao X, Cai B, Ding Q, Huang Y, Li Y, Li Y, Niu Y, Lei A, Kou Q, Huang X, Petersen B, Ma B, Chen Y, Wang X. Zhou S, et al. Among authors: yu h. Reprod Fertil Dev. 2018 Nov;30(12):1616-1621. doi: 10.1071/RD18086. Reprod Fertil Dev. 2018. PMID: 31039970

5

Base pair editing in goat: nonsense codon introgression into FGF5 results in longer hair.

Li G, Zhou S, Li C, Cai B, Yu H, Ma B, Huang Y, Ding Y, Liu Y, Ding Q, He C, Zhou J, Wang Y, Zhou G, Li Y, Yan Y, Hua J, Petersen B, Jiang Y, Sonstegard T, Huang X, Chen Y, Wang X. Li G, et al. Among authors: yu h. FEBS J. 2019 Dec;286(23):4675-4692. doi: 10.1111/febs.14983. Epub 2019 Jul 23. FEBS J. 2019. PMID: 31276295 Free article.

6

CRISPR/Cas9-mediated MSTN disruption and heritable mutagenesis in goats causes increased body mass.

Wang X, Niu Y, Zhou J, Zhu H, Ma B, Yu H, Yan H, Hua J, Huang X, Qu L, Chen Y. Wang X, et al. Among authors: yu h. Anim Genet. 2018 Feb;49(1):43-51. doi: 10.1111/age.12626. Anim Genet. 2018. PMID: 29446146

7

Porcine Zygote Injection with Cas9/sgRNA Results in DMD-Modified Pig with Muscle Dystrophy.

Yu HH, Zhao H, Qing YB, Pan WR, Jia BY, Zhao HY, Huang XX, Wei HJ. Yu HH, et al. Int J Mol Sci. 2016 Oct 9;17(10):1668. doi: 10.3390/ijms17101668. Int J Mol Sci. 2016. PMID: 27735844 Free PMC article.

8

Correction: Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers.

Wang X, Cai B, Zhou J, Zhu H, Niu Y, Ma B, Yu H, Lei A, Yan H, Shen Q, Shi L, Zhao X, Hua J, Huang X, Qu L, Chen Y. Wang X, et al. Among authors: yu h. PLoS One. 2016 Nov 22;11(11):e0167322. doi: 10.1371/journal.pone.0167322. eCollection 2016. PLoS One. 2016. PMID: 27875586 Free PMC article.

9

Highly efficient generation of sheep with a defined FecB^B mutation via adenine base editing.

Zhou S, Ding Y, Liu J, Liu Y, Zhao X, Li G, Zhang C, Li C, Wang Y, Kalds P, Gao Y, Zong B, Huang X, Huang S, Yu H, Kou Q, Petersen B, Huang X, Wang X, Ma B, Chen Y. Zhou S, et al. Among authors: yu h. Genet Sel Evol. 2020 Jul 1;52(1):35. doi: 10.1186/s12711-020-00554-6. Genet Sel Evol. 2020. PMID: 32611306 Free PMC article.

10

Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.

Yu H, Long W, Zhang X, Xu K, Guo J, Zhao H, Li H, Qing Y, Pan W, Jia B, Zhao HY, Huang X, Wei HJ. Yu H, et al. J Transl Med. 2018 Feb 27;16(1):41. doi: 10.1186/s12967-018-1409-7. J Transl Med. 2018. PMID: 29482569 Free PMC article.

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