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Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.
Pellegrino M, Mancini F, Lucà R, Coletti A, Giacchè N, Manni I, Arisi I, Florenzano F, Teveroni E, Buttarelli M, Fici L, Brandi R, Bruno T, Fanciulli M, D'Onofrio M, Piaggio G, Pellicciari R, Pontecorvi A, Marine JC, Macchiarulo A, Moretti F. Pellegrino M, et al. Among authors: pellicciari r. Cancer Res. 2015 Nov 1;75(21):4560-72. doi: 10.1158/0008-5472.CAN-15-0439. Epub 2015 Sep 10. Cancer Res. 2015. PMID: 26359458
MDM2/MDMX inhibitor peptide: WO2008106507.
Macchiarulo A, Pellicciari R. Macchiarulo A, et al. Among authors: pellicciari r. Expert Opin Ther Pat. 2009 May;19(5):721-6. doi: 10.1517/13543770902755137. Expert Opin Ther Pat. 2009. PMID: 19441944
Puzzling over MDM4-p53 network.
Mancini F, Di Conza G, Monti O, Macchiarulo A, Pellicciari R, Pontecorvi A, Moretti F. Mancini F, et al. Among authors: pellicciari r. Int J Biochem Cell Biol. 2010 Jul;42(7):1080-3. doi: 10.1016/j.biocel.2010.04.010. Epub 2010 Apr 22. Int J Biochem Cell Biol. 2010. PMID: 20417304 Review.
277 results