Takeuchi T - Search Results

1

Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-β Amyloidogenesis in Alzheimer Disease.

Itakura M, Nakajima H, Kubo T, Semi Y, Kume S, Higashida S, Kaneshige A, Kuwamura M, Harada N, Kita A, Azuma YT, Yamaji R, Inui T, Takeuchi T. Itakura M, et al. Among authors: takeuchi t. J Biol Chem. 2015 Oct 23;290(43):26072-87. doi: 10.1074/jbc.M115.669291. Epub 2015 Sep 10. J Biol Chem. 2015. PMID: 26359500 Free PMC article.

2

The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death.

Nakajima H, Amano W, Fujita A, Fukuhara A, Azuma YT, Hata F, Inui T, Takeuchi T. Nakajima H, et al. Among authors: takeuchi t. J Biol Chem. 2007 Sep 7;282(36):26562-74. doi: 10.1074/jbc.M704199200. Epub 2007 Jul 5. J Biol Chem. 2007. PMID: 17613523 Free article.

3

Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death.

Nakajima H, Amano W, Kubo T, Fukuhara A, Ihara H, Azuma YT, Tajima H, Inui T, Sawa A, Takeuchi T. Nakajima H, et al. Among authors: takeuchi t. J Biol Chem. 2009 Dec 4;284(49):34331-41. doi: 10.1074/jbc.M109.027698. Epub 2009 Oct 16. J Biol Chem. 2009. PMID: 19837666 Free PMC article.

4

An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells.

Nakajima H, Amano W, Fukuhara A, Kubo T, Misaki S, Azuma YT, Inui T, Takeuchi T. Nakajima H, et al. Among authors: takeuchi t. Biochem Biophys Res Commun. 2009 Dec 18;390(3):1066-71. doi: 10.1016/j.bbrc.2009.10.118. Epub 2009 Oct 27. Biochem Biophys Res Commun. 2009. PMID: 19874799

5

Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke.

Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, Shahani N, Itakura M, Ono Y, Azuma YT, Inui T, Kamiya A, Sawa A, Takeuchi T. Nakajima H, et al. Among authors: takeuchi t. J Biol Chem. 2015 Jun 5;290(23):14493-503. doi: 10.1074/jbc.M114.635607. Epub 2015 Apr 16. J Biol Chem. 2015. PMID: 25882840 Free PMC article.

6

Glyceraldehyde-3-phosphate dehydrogenase aggregation inhibitor peptide: A potential therapeutic strategy against oxidative stress-induced cell death.

Itakura M, Nakajima H, Semi Y, Higashida S, Azuma YT, Takeuchi T. Itakura M, et al. Among authors: takeuchi t. Biochem Biophys Res Commun. 2015 Nov 13;467(2):373-6. doi: 10.1016/j.bbrc.2015.09.150. Epub 2015 Oct 6. Biochem Biophys Res Commun. 2015. PMID: 26431872

7

Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death.

Kubo T, Nakajima H, Nakatsuji M, Itakura M, Kaneshige A, Azuma YT, Inui T, Takeuchi T. Kubo T, et al. Among authors: takeuchi t. Nitric Oxide. 2016 Feb 29;53:13-21. doi: 10.1016/j.niox.2015.12.005. Epub 2015 Dec 25. Nitric Oxide. 2016. PMID: 26725192 Free article.

8

Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death.

Nakajima H, Itakura M, Kubo T, Kaneshige A, Harada N, Izawa T, Azuma YT, Kuwamura M, Yamaji R, Takeuchi T. Nakajima H, et al. Among authors: takeuchi t. J Biol Chem. 2017 Mar 17;292(11):4727-4742. doi: 10.1074/jbc.M116.759084. Epub 2017 Feb 6. J Biol Chem. 2017. PMID: 28167533 Free PMC article.

9

A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain.

Nakajima H, Kubo T, Semi Y, Itakura M, Kuwamura M, Izawa T, Azuma YT, Takeuchi T. Nakajima H, et al. Among authors: takeuchi t. J Biotechnol. 2012 Jan 20;157(2):326-33. doi: 10.1016/j.jbiotec.2011.10.003. Epub 2011 Nov 6. J Biotechnol. 2012. PMID: 22079868

10

IL-19 as a potential therapeutic in autoimmune and inflammatory diseases.

Azuma YT, Nakajima H, Takeuchi T. Azuma YT, et al. Among authors: takeuchi t. Curr Pharm Des. 2011 Nov;17(34):3776-80. doi: 10.2174/138161211798357845. Curr Pharm Des. 2011. PMID: 22103848 Review.

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