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Synthesis of an Endogenous Steroidal Na Pump Inhibitor Marinobufagenin, Implicated in Human Cardiovascular Diseases, Is Initiated by CYP27A1 via Bile Acid Pathway.
Fedorova OV, Zernetkina VI, Shilova VY, Grigorova YN, Juhasz O, Wei W, Marshall CA, Lakatta EG, Bagrov AY. Fedorova OV, et al. Among authors: shilova vy. Circ Cardiovasc Genet. 2015 Oct;8(5):736-45. doi: 10.1161/CIRCGENETICS.115.001217. Epub 2015 Sep 15. Circ Cardiovasc Genet. 2015. PMID: 26374826 Free PMC article.
Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension.
Zhang Y, Wei W, Shilova V, Petrashevskaya NN, Zernetkina VI, Grigorova YN, Marshall CA, Fenner RC, Lehrmann E, Wood WH 3rd, Becker KG, Lakatta EG, Bagrov AY, Fedorova OV. Zhang Y, et al. J Am Heart Assoc. 2019 Oct 15;8(20):e012138. doi: 10.1161/JAHA.119.012138. Epub 2019 Oct 2. J Am Heart Assoc. 2019. PMID: 31576777 Free PMC article.
Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro-Fibrotic Signaling.
Haller ST, Yan Y, Drummond CA, Xie J, Tian J, Kennedy DJ, Shilova VY, Xie Z, Liu J, Cooper CJ, Malhotra D, Shapiro JI, Fedorova OV, Bagrov AY. Haller ST, et al. Among authors: shilova vy. J Am Heart Assoc. 2016 Sep 30;5(10):e004106. doi: 10.1161/JAHA.116.004106. J Am Heart Assoc. 2016. PMID: 27694325 Free PMC article.
Deletions of the cystathionine-β-synthase (CBS) and cystathionine-γ-lyase (CSE) genes, involved in the control of hydrogen sulfide biosynthesis, significantly affect lifespan and fitness components of Drosophila melanogaster.
Shaposhnikov MV, Zakluta AS, Zemskaya NV, Guvatova ZG, Shilova VY, Yakovleva DV, Gorbunova AA, Koval LA, Ulyasheva NS, Evgen'ev MB, Zatsepina OG, Moskalev AA. Shaposhnikov MV, et al. Among authors: shilova vy. Mech Ageing Dev. 2022 Apr;203:111656. doi: 10.1016/j.mad.2022.111656. Epub 2022 Mar 2. Mech Ageing Dev. 2022. PMID: 35247392
14 results