Khom S - Search Results

1

Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis.

Luger D, Poli G, Wieder M, Stadler M, Ke S, Ernst M, Hohaus A, Linder T, Seidel T, Langer T, Khom S, Hering S. Luger D, et al. Among authors: khom s. Br J Pharmacol. 2015 Nov;172(22):5403-13. doi: 10.1111/bph.13329. Epub 2015 Oct 25. Br J Pharmacol. 2015. PMID: 26375408 Free PMC article.

2

Pharmacological properties of GABAA receptors containing gamma1 subunits.

Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S. Khom S, et al. Mol Pharmacol. 2006 Feb;69(2):640-9. doi: 10.1124/mol.105.017236. Epub 2005 Nov 4. Mol Pharmacol. 2006. PMID: 16272224

3

Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity.

Khom S, Baburin I, Timin E, Hohaus A, Trauner G, Kopp B, Hering S. Khom S, et al. Neuropharmacology. 2007 Jul;53(1):178-87. doi: 10.1016/j.neuropharm.2007.04.018. Epub 2007 May 13. Neuropharmacology. 2007. PMID: 17585957

4

Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid.

Trauner G, Khom S, Baburin I, Benedek B, Hering S, Kopp B. Trauner G, et al. Among authors: khom s. Planta Med. 2008 Jan;74(1):19-24. doi: 10.1055/s-2007-993761. Epub 2007 Dec 19. Planta Med. 2008. PMID: 18095218

5

HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes.

Kim HJ, Baburin I, Khom S, Hering S, Hamburger M. Kim HJ, et al. Among authors: khom s. Planta Med. 2008 Apr;74(5):521-6. doi: 10.1055/s-2008-1074491. Planta Med. 2008. PMID: 18543148 Free PMC article.

6

Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits.

Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Baburin I, et al. Among authors: khom s. Br J Pharmacol. 2008 Oct;155(3):424-33. doi: 10.1038/bjp.2008.271. Epub 2008 Jul 7. Br J Pharmacol. 2008. PMID: 18604239 Free PMC article.

7

Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization.

Khom S, Strommer B, Ramharter J, Schwarz T, Schwarzer C, Erker T, Ecker GF, Mulzer J, Hering S. Khom S, et al. Br J Pharmacol. 2010 Sep;161(1):65-78. doi: 10.1111/j.1476-5381.2010.00865.x. Br J Pharmacol. 2010. PMID: 20718740 Free PMC article.

8

Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa.

Cicek SS, Khom S, Taferner B, Hering S, Stuppner H. Cicek SS, et al. Among authors: khom s. J Nat Prod. 2010 Dec 27;73(12):2024-8. doi: 10.1021/np100479w. Epub 2010 Nov 17. J Nat Prod. 2010. PMID: 21082802

9

Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice.

Zaugg J, Khom S, Eigenmann D, Baburin I, Hamburger M, Hering S. Zaugg J, et al. Among authors: khom s. J Nat Prod. 2011 Aug 26;74(8):1764-72. doi: 10.1021/np200317p. Epub 2011 Jul 27. J Nat Prod. 2011. PMID: 21793559

10

GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus.

Singhuber J, Baburin I, Khom S, Zehl M, Urban E, Hering S, Kopp B. Singhuber J, et al. Among authors: khom s. Planta Med. 2012 Mar;78(5):455-8. doi: 10.1055/s-0031-1298174. Epub 2012 Jan 23. Planta Med. 2012. PMID: 22271080

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