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HIV-1 variants are archived throughout infection and persist in the reservoir.
Brooks K, Jones BR, Dilernia DA, Wilkins DJ, Claiborne DT, McInally S, Gilmour J, Kilembe W, Joy JB, Allen SA, Brumme ZL, Hunter E. Brooks K, et al. Among authors: dilernia da. PLoS Pathog. 2020 Jun 3;16(6):e1008378. doi: 10.1371/journal.ppat.1008378. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32492044 Free PMC article. Clinical Trial.
HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses.
Erdmann N, Du VY, Carlson J, Schaefer M, Jureka A, Sterrett S, Yue L, Dilernia D, Lakhi S, Tang J, Sidney J, Gilmour J, Allen S, Hunter E, Heath S, Bansal A, Goepfert PA. Erdmann N, et al. PLoS Pathog. 2015 Aug 24;11(8):e1005111. doi: 10.1371/journal.ppat.1005111. eCollection 2015 Aug. PLoS Pathog. 2015. PMID: 26302050 Free PMC article.
Infection with multiple HIV-1 founder variants is associated with lower viral replicative capacity, faster CD4+ T cell decline and increased immune activation during acute infection.
Macharia GN, Yue L, Staller E, Dilernia D, Wilkins D, Song H, McGowan E, King D, Fast P, Imami N, Price MA, Sanders EJ, Hunter E, Gilmour J. Macharia GN, et al. PLoS Pathog. 2020 Sep 4;16(9):e1008853. doi: 10.1371/journal.ppat.1008853. eCollection 2020 Sep. PLoS Pathog. 2020. PMID: 32886726 Free PMC article.
Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts.
Umviligihozo G, Muok E, Nyirimihigo Gisa E, Xu R, Dilernia D, Herard K, Song H, Qin Q, Bizimana J, Farmer P, Hare J, Gilmour J, Allen S, Karita E, Hunter E, Yue L. Umviligihozo G, et al. Front Microbiol. 2021 Oct 7;12:734929. doi: 10.3389/fmicb.2021.734929. eCollection 2021. Front Microbiol. 2021. PMID: 34690973 Free PMC article.
Characterization of Near Full-Length Transmitted/Founder HIV-1 Subtype D and A/D Recombinant Genomes in a Heterosexual Ugandan Population (2006-2011).
Balinda SN, Kapaata A, Xu R, Salazar MG, Mezzell AT, Qin Q, Herard K, Dilernia D, Kamali A, Ruzagira E, Kibengo FM, Song H, Ochsenbauer C, Salazar-Gonzalez JF, Gilmour J, Hunter E, Yue L, Kaleebu P. Balinda SN, et al. Viruses. 2022 Feb 7;14(2):334. doi: 10.3390/v14020334. Viruses. 2022. PMID: 35215928 Free PMC article.
Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression.
Mónaco DC, Dilernia DA, Fiore-Gartland A, Yu T, Prince JL, Dennis KK, Qin K, Schaefer M, Claiborne DT, Kilembe W, Tang J, Price MA, Farmer P, Gilmour J, Bansal A, Allen S, Goepfert P, Hunter E. Mónaco DC, et al. Among authors: dilernia da. J Exp Med. 2016 Sep 19;213(10):2049-63. doi: 10.1084/jem.20151984. Epub 2016 Aug 22. J Exp Med. 2016. PMID: 27551154 Free PMC article.
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