Cromwell MEM - Search Results

1

Protein Aggregation in Frozen Trehalose Formulations: Effects of Composition, Cooling Rate, and Storage Temperature.

Connolly BD, Le L, Patapoff TW, Cromwell MEM, Moore JMR, Lam P. Connolly BD, et al. Among authors: cromwell mem. J Pharm Sci. 2015 Dec;104(12):4170-4184. doi: 10.1002/jps.24646. Epub 2015 Sep 23. J Pharm Sci. 2015. PMID: 26398200

2

Kinetics and thermodynamics of dimer formation and dissociation for a recombinant humanized monoclonal antibody to vascular endothelial growth factor.

Moore JM, Patapoff TW, Cromwell ME. Moore JM, et al. Biochemistry. 1999 Oct 19;38(42):13960-7. doi: 10.1021/bi9905516. Biochemistry. 1999. PMID: 10529242

3

A low-volume, short-path length dynamic light scattering sample cell for highly turbid suspensions.

Patapoff TW, Tani TH, Cromwell ME. Patapoff TW, et al. Anal Biochem. 1999 Jun 1;270(2):338-40. doi: 10.1006/abio.1999.4108. Anal Biochem. 1999. PMID: 10334855 No abstract available.

4

In-use physicochemical and microbiological stability of biological parenteral products.

Ricci MS, Frazier M, Moore J, Cromwell M, Galush WJ, Patel AR, Adler M, Altenburger U, Grauschopf U, Goldbach P, Fast JL, Krämer I, Mahler HC. Ricci MS, et al. Am J Health Syst Pharm. 2015 Mar 1;72(5):396-407. doi: 10.2146/ajhp140098. Am J Health Syst Pharm. 2015. PMID: 25694415 No abstract available.

5

Effect of individual Fc methionine oxidation on FcRn binding: Met252 oxidation impairs FcRn binding more profoundly than Met428 oxidation.

Gao X, Ji JA, Veeravalli K, Wang YJ, Zhang T, Mcgreevy W, Zheng K, Kelley RF, Laird MW, Liu J, Cromwell M. Gao X, et al. J Pharm Sci. 2015 Feb;104(2):368-77. doi: 10.1002/jps.24136. Epub 2014 Aug 29. J Pharm Sci. 2015. PMID: 25175600

6

Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue.

Rubas W, Cromwell ME, Shahrokh Z, Villagran J, Nguyen TN, Wellton M, Nguyen TH, Mrsny RJ. Rubas W, et al. J Pharm Sci. 1996 Feb;85(2):165-9. doi: 10.1021/js950267+. J Pharm Sci. 1996. PMID: 8683442

7

Concluding summary: proceedings of the AAPS Biotec open forum on "aggregation of protein therapeutics".

Shire SJ, Cromwell M, Liu J. Shire SJ, et al. AAPS J. 2006;8(4):E729-30. doi: 10.1208/aapsj080482. AAPS J. 2006. PMID: 18473180 Free PMC article. No abstract available.

8

An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics.

Singh SK, Afonina N, Awwad M, Bechtold-Peters K, Blue JT, Chou D, Cromwell M, Krause HJ, Mahler HC, Meyer BK, Narhi L, Nesta DP, Spitznagel T. Singh SK, et al. J Pharm Sci. 2010 Aug;99(8):3302-21. doi: 10.1002/jps.22097. J Pharm Sci. 2010. PMID: 20310025 Review.

9

Protein aggregation and bioprocessing.

Cromwell ME, Hilario E, Jacobson F. Cromwell ME, et al. AAPS J. 2006 Sep 15;8(3):E572-9. doi: 10.1208/aapsj080366. AAPS J. 2006. PMID: 17025275 Free PMC article. Review.

10

An integrated method to determine epithelial transport and bioactivity of oral drug candidates in vitro.

Rubas W, Cromwell ME, Mrsny RJ, Ingle G, Elias KA. Rubas W, et al. Pharm Res. 1996 Jan;13(1):23-6. doi: 10.1023/a:1016060729594. Pharm Res. 1996. PMID: 8668673 No abstract available.

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