Marek GJ - Search Results

1

APOE-ɛ4 Carrier Status and Donepezil Response in Patients with Alzheimer's Disease.

Waring JF, Tang Q, Robieson WZ, King DP, Das U, Dubow J, Dutta S, Marek GJ, Gault LM. Waring JF, et al. Among authors: marek gj. J Alzheimers Dis. 2015;47(1):137-48. doi: 10.3233/JAD-142589. J Alzheimers Dis. 2015. PMID: 26402762 Free PMC article. Clinical Trial.

2

Population pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 in healthy volunteers following single and multiple dose regimens.

An G, Liu W, Katz DA, Marek GJ, Awni W, Dutta S. An G, et al. Among authors: marek gj. Biopharm Drug Dispos. 2014 Oct;35(7):417-29. doi: 10.1002/bdd.1912. Epub 2014 Aug 30. Biopharm Drug Dispos. 2014. PMID: 25041811 Clinical Trial.

3

LY-2140023, a prodrug of the group II metabotropic glutamate receptor agonist LY-404039 for the potential treatment of schizophrenia.

Mezler M, Geneste H, Gault L, Marek GJ. Mezler M, et al. Among authors: marek gj. Curr Opin Investig Drugs. 2010 Jul;11(7):833-45. Curr Opin Investig Drugs. 2010. PMID: 20571979 Clinical Trial.

4

Efficacy and safety evaluation of HSD-1 inhibitor ABT-384 in Alzheimer's disease.

Marek GJ, Katz DA, Meier A, Greco N 4th, Zhang W, Liu W, Lenz RA. Marek GJ, et al. Alzheimers Dement. 2014 Oct;10(5 Suppl):S364-73. doi: 10.1016/j.jalz.2013.09.010. Epub 2014 Jan 10. Alzheimers Dement. 2014. PMID: 24418055 Clinical Trial.

5

Effect of ketoconazole on the pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study.

An G, Liu W, Katz DA, Marek G, Awni W, Dutta S. An G, et al. Drug Metab Dispos. 2013 May;41(5):1035-45. doi: 10.1124/dmd.112.049742. Epub 2013 Feb 19. Drug Metab Dispos. 2013. PMID: 23431112

6

Clinical Safety, Pharmacokinetics, and Pharmacodynamics of the 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor ABT-384 in Healthy Volunteers and Elderly Adults.

Liu W, Katz DA, Locke C, Daszkowski D, Wang Y, Rieser MJ, Awni W, Marek GJ, Dutta S. Liu W, et al. Among authors: marek gj. Clin Pharmacol Drug Dev. 2013 Apr;2(2):133-51. doi: 10.1002/cpdd.5. Epub 2013 Feb 21. Clin Pharmacol Drug Dev. 2013. PMID: 27121668

7

Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals.

Chin CL, Upadhyay J, Marek GJ, Baker SJ, Zhang M, Mezler M, Fox GB, Day M. Chin CL, et al. Among authors: marek gj. J Pharmacol Exp Ther. 2011 Mar;336(3):709-15. doi: 10.1124/jpet.110.173880. Epub 2010 Dec 20. J Pharmacol Exp Ther. 2011. PMID: 21172908

8

Effects of a positive allosteric modulator of group II metabotropic glutamate receptors, LY487379, on cognitive flexibility and impulsive-like responding in rats.

Nikiforuk A, Popik P, Drescher KU, van Gaalen M, Relo AL, Mezler M, Marek G, Schoemaker H, Gross G, Bespalov A. Nikiforuk A, et al. J Pharmacol Exp Ther. 2010 Dec;335(3):665-73. doi: 10.1124/jpet.110.170506. Epub 2010 Aug 25. J Pharmacol Exp Ther. 2010. PMID: 20739457

9

Heterocomplex formation of 5-HT2A-mGlu2 and its relevance for cellular signaling cascades.

Delille HK, Becker JM, Burkhardt S, Bleher B, Terstappen GC, Schmidt M, Meyer AH, Unger L, Marek GJ, Mezler M. Delille HK, et al. Among authors: marek gj. Neuropharmacology. 2012 Jun;62(7):2184-91. doi: 10.1016/j.neuropharm.2012.01.010. Epub 2012 Jan 25. Neuropharmacology. 2012. PMID: 22300836

10

The two faces of the pharmacological interaction of mGlu2 and 5-HT₂A - relevance of receptor heterocomplexes and interaction through functional brain pathways.

Delille HK, Mezler M, Marek GJ. Delille HK, et al. Among authors: marek gj. Neuropharmacology. 2013 Jul;70:296-305. doi: 10.1016/j.neuropharm.2013.02.005. Epub 2013 Mar 4. Neuropharmacology. 2013. PMID: 23466331 Review.

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