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F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103.
Etiévant C, Kruczynski A, Barret JM, Perrin D, van Hille B, Guminski Y, Hill BT. Etiévant C, et al. Among authors: kruczynski a. Cancer Chemother Pharmacol. 2000;46(2):101-13. doi: 10.1007/s002800000133. Cancer Chemother Pharmacol. 2000. PMID: 10972479
Antitumor pharmacology -- quo vadis?
Bailly C, Barret JM, Kruczynski A. Bailly C, et al. Among authors: kruczynski a. Curr Med Chem Anticancer Agents. 2004 Sep;4(5):389-91. doi: 10.2174/1568011043352849. Curr Med Chem Anticancer Agents. 2004. PMID: 15379689 Review.
Synthesis and biological evaluation of bengacarboline derivatives.
Pouilhès A, Kouklovsky C, Langlois Y, Baltaze JP, Vispé S, Annereau JP, Barret JM, Kruczynski A, Bailly C. Pouilhès A, et al. Among authors: kruczynski a. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1212-6. doi: 10.1016/j.bmcl.2007.11.113. Epub 2007 Dec 4. Bioorg Med Chem Lett. 2008. PMID: 18083028
75 results