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An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.
Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM. Clayton T, et al. Among authors: cook jm. Curr Med Chem. 2007;14(26):2755-75. doi: 10.2174/092986707782360097. Curr Med Chem. 2007. PMID: 18045122 Review.
Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABA(A) receptors.
Joksimović S, Divljaković J, Van Linn ML, Varagic Z, Brajković G, Milinković MM, Yin W, Timić T, Sieghart W, Cook JM, Savić MM. Joksimović S, et al. Among authors: cook jm. Eur Neuropsychopharmacol. 2013 May;23(5):390-9. doi: 10.1016/j.euroneuro.2012.05.003. Epub 2012 May 26. Eur Neuropsychopharmacol. 2013. PMID: 22633616 Free PMC article.
Insights into functional pharmacology of α₁ GABA(A) receptors: how much does partial activation at the benzodiazepine site matter?
Joksimović S, Varagic Z, Kovačević J, Van Linn M, Milić M, Rallapalli S, Timić T, Sieghart W, Cook JM, Savić MM. Joksimović S, et al. Among authors: cook jm. Psychopharmacology (Berl). 2013 Nov;230(1):113-23. doi: 10.1007/s00213-013-3143-4. Epub 2013 May 18. Psychopharmacology (Berl). 2013. PMID: 23685860 Free PMC article.
Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects.
Obradović ALj, Joksimović S, Poe MM, Ramerstorfer J, Varagic Z, Namjoshi O, Batinić B, Radulović T, Marković B, Roth BL, Sieghart W, Cook JM, Savić MM. Obradović ALj, et al. Among authors: cook jm. Brain Res. 2014 Mar 20;1554:36-48. doi: 10.1016/j.brainres.2014.01.036. Epub 2014 Jan 25. Brain Res. 2014. PMID: 24472579 Free PMC article.
626 results