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Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity.
Serrels A, Lund T, Serrels B, Byron A, McPherson RC, von Kriegsheim A, Gómez-Cuadrado L, Canel M, Muir M, Ring JE, Maniati E, Sims AH, Pachter JA, Brunton VG, Gilbert N, Anderton SM, Nibbs RJ, Frame MC. Serrels A, et al. Among authors: mcpherson rc. Cell. 2015 Sep 24;163(1):160-73. doi: 10.1016/j.cell.2015.09.001. Cell. 2015. PMID: 26406376 Free PMC article.
Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.
Colbeck EJ, Hindley JP, Smart K, Jones E, Bloom A, Bridgeman H, McPherson RC, Turner DG, Ladell K, Price DA, O'Connor RA, Anderton SM, Godkin AJ, Gallimore AM. Colbeck EJ, et al. Among authors: mcpherson rc. Oncotarget. 2015 Sep 22;6(28):24649-59. doi: 10.18632/oncotarget.5584. Oncotarget. 2015. PMID: 26433463 Free PMC article.
33 results