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Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
De Savi C, Bradbury RH, Rabow AA, Norman RA, de Almeida C, Andrews DM, Ballard P, Buttar D, Callis RJ, Currie GS, Curwen JO, Davies CD, Donald CS, Feron LJ, Gingell H, Glossop SC, Hayter BR, Hussain S, Karoutchi G, Lamont SG, MacFaul P, Moss TA, Pearson SE, Tonge M, Walker GE, Weir HM, Wilson Z. De Savi C, et al. Among authors: hussain s. J Med Chem. 2015 Oct 22;58(20):8128-40. doi: 10.1021/acs.jmedchem.5b00984. Epub 2015 Oct 7. J Med Chem. 2015. PMID: 26407012
Discovery of novel Jak2-Stat pathway inhibitors with extended residence time on target.
Guan H, Lamb ML, Peng B, Huang S, Degrace N, Read J, Hussain S, Wu J, Rivard C, Alimzhanov M, Bebernitz G, Bell K, Ye M, Zinda M, Ioannidis S. Guan H, et al. Among authors: hussain s. Bioorg Med Chem Lett. 2013 May 15;23(10):3105-10. doi: 10.1016/j.bmcl.2013.02.111. Epub 2013 Mar 7. Bioorg Med Chem Lett. 2013. PMID: 23562594
A Cross-Sectional Serological Study to Assess the Prevalence and Risk Factors of Anaplasmosis in Dromedary Camels in Punjab, Pakistan.
Abbas MZ, Ghafoor M, Hussain MH, Alvi MA, Jamil T, Sajid MS, Aslam M, Hassan A, Hussain S, Hafeez MA, Ullah MI, Khan I, Ashfaq K, Muhammad G, Mertens-Scholz K, Neubauer H, El-Adawy H, Saqib M. Abbas MZ, et al. Among authors: hussain s. Vet Sci. 2024 Dec 16;11(12):657. doi: 10.3390/vetsci11120657. Vet Sci. 2024. PMID: 39728997
Brief Report: Protease Inhibitors Versus Nonnucleoside Reverse Transcriptase Inhibitors and the Risk of Cancer Among People With HIV.
Coburn SB, Pimentel N, Leyden W, Kitahata M, Moore RD, Althoff KN, Gill MJ, Lang R, Horberg MA, D'Souza G, Hussain SK, Dubrow R, Novak RM, Rabkin CS, Park LS, Sterling TR, Neugebauer RS, Silverberg MJ; North American AIDS Cohort Collaboration on Research and Design of the International Epidemiologic Databases to Evaluate AIDS. Coburn SB, et al. Among authors: hussain sk. J Acquir Immune Defic Syndr. 2024 Aug;96(4):393-398. doi: 10.1097/QAI.0000000000003436. J Acquir Immune Defic Syndr. 2024. PMID: 39720558
6,261 results