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Heme-induced contractile dysfunction in human cardiomyocytes caused by oxidant damage to thick filament proteins.
Alvarado G, Jeney V, Tóth A, Csősz É, Kalló G, Huynh AT, Hajnal C, Kalász J, Pásztor ET, Édes I, Gram M, Akerström B, Smith A, Eaton JW, Balla G, Papp Z, Balla J. Alvarado G, et al. Among authors: smith a. Free Radic Biol Med. 2015 Dec;89:248-62. doi: 10.1016/j.freeradbiomed.2015.07.158. Epub 2015 Sep 25. Free Radic Biol Med. 2015. PMID: 26409224
Red cells, hemoglobin, heme, iron, and atherogenesis.
Nagy E, Eaton JW, Jeney V, Soares MP, Varga Z, Galajda Z, Szentmiklósi J, Méhes G, Csonka T, Smith A, Vercellotti GM, Balla G, Balla J. Nagy E, et al. Among authors: smith a. Arterioscler Thromb Vasc Biol. 2010 Jul;30(7):1347-53. doi: 10.1161/ATVBAHA.110.206433. Epub 2010 Apr 8. Arterioscler Thromb Vasc Biol. 2010. PMID: 20378845 Free PMC article.
A central role for free heme in the pathogenesis of severe sepsis.
Larsen R, Gozzelino R, Jeney V, Tokaji L, Bozza FA, Japiassú AM, Bonaparte D, Cavalcante MM, Chora A, Ferreira A, Marguti I, Cardoso S, Sepúlveda N, Smith A, Soares MP. Larsen R, et al. Among authors: smith a. Sci Transl Med. 2010 Sep 29;2(51):51ra71. doi: 10.1126/scitranslmed.3001118. Sci Transl Med. 2010. PMID: 20881280
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