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Page 1
Compound- and sex-specific effects on programming of energy and immune homeostasis in adult C57BL/6JxFVB mice after perinatal TCDD and PCB 153.
van Esterik JC, Verharen HW, Hodemaekers HM, Gremmer ER, Nagarajah B, Kamstra JH, Dollé ME, Legler J, van der Ven LT. van Esterik JC, et al. Among authors: nagarajah b. Toxicol Appl Pharmacol. 2015 Dec 1;289(2):262-75. doi: 10.1016/j.taap.2015.09.017. Epub 2015 Sep 28. Toxicol Appl Pharmacol. 2015. PMID: 26415833
The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency.
Reiling E, Dollé ME, Youssef SA, Lee M, Nagarajah B, Roodbergen M, de With P, de Bruin A, Hoeijmakers JH, Vijg J, van Steeg H, Hasty P. Reiling E, et al. Among authors: nagarajah b. PLoS One. 2014 Apr 16;9(4):e93568. doi: 10.1371/journal.pone.0093568. eCollection 2014. PLoS One. 2014. PMID: 24740260 Free PMC article.
Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice.
Vermeij WP, Dollé ME, Reiling E, Jaarsma D, Payan-Gomez C, Bombardieri CR, Wu H, Roks AJ, Botter SM, van der Eerden BC, Youssef SA, Kuiper RV, Nagarajah B, van Oostrom CT, Brandt RM, Barnhoorn S, Imholz S, Pennings JL, de Bruin A, Gyenis Á, Pothof J, Vijg J, van Steeg H, Hoeijmakers JH. Vermeij WP, et al. Among authors: nagarajah b. Nature. 2016 Sep 15;537(7620):427-431. doi: 10.1038/nature19329. Epub 2016 Aug 24. Nature. 2016. PMID: 27556946 Free PMC article.
Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. Birkisdóttir MB, et al. Among authors: nagarajah b. Front Aging. 2022 Nov 23;3:1086552. doi: 10.3389/fragi.2022.1086552. eCollection 2022. Front Aging. 2022. PMID: 36506463 Free PMC article.
Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice.
Birkisdóttir MB, Jaarsma D, Brandt RMC, Barnhoorn S, van Vliet N, Imholz S, van Oostrom CT, Nagarajah B, Portilla Fernández E, Roks AJM, Elgersma Y, van Steeg H, Ferreira JA, Pennings JLA, Hoeijmakers JHJ, Vermeij WP, Dollé MET. Birkisdóttir MB, et al. Among authors: nagarajah b. Aging Cell. 2021 Feb;20(2):e13302. doi: 10.1111/acel.13302. Epub 2021 Jan 23. Aging Cell. 2021. PMID: 33484480 Free PMC article.
The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Birkisdóttir MB, van Galen I, Brandt RMC, Barnhoorn S, van Vliet N, van Dijk C, Nagarajah B, Imholz S, van Oostrom CT, Reiling E, Gyenis Á, Mastroberardino PG, Jaarsma D, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP. Birkisdóttir MB, et al. Among authors: nagarajah b. Front Aging. 2022 Oct 12;3:1005322. doi: 10.3389/fragi.2022.1005322. eCollection 2022. Front Aging. 2022. PMID: 36313181 Free PMC article.