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Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vašíčková K, Kolářová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Ešner M, Jaroš J, Hampl A, Krejčí L, Paruch K, Souček K. Samadder P, et al. Among authors: strakova n. Mol Cancer Ther. 2017 Sep;16(9):1831-1842. doi: 10.1158/1535-7163.MCT-17-0018. Epub 2017 Jun 15. Mol Cancer Ther. 2017. PMID: 28619751
Phospholipid profiling enables to discriminate tumor- and non-tumor-derived human colon epithelial cells: Phospholipidome similarities and differences in colon cancer cell lines and in patient-derived cell samples.
Hofmanová J, Slavík J, Ovesná P, Tylichová Z, Dušek L, Straková N, Vaculová AH, Ciganek M, Kala Z, Jíra M, Penka I, Kyclová J, Kolář Z, Kozubík A, Machala M, Vondráček J. Hofmanová J, et al. Among authors: strakova n. PLoS One. 2020 Jan 30;15(1):e0228010. doi: 10.1371/journal.pone.0228010. eCollection 2020. PLoS One. 2020. PMID: 31999740 Free PMC article.
29 results