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Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells.
Tang Y, Yacoub A, Hamed HA, Poklepovic A, Tye G, Grant S, Dent P. Tang Y, et al. Among authors: poklepovic a. Cancer Biol Ther. 2012 May;13(7):567-74. doi: 10.4161/cbt.19771. Epub 2012 May 1. Cancer Biol Ther. 2012. PMID: 22406992 Free PMC article.
Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling.
Bareford MD, Hamed HA, Allegood J, Cruickshanks N, Poklepovic A, Park MA, Ogretmen B, Spiegel S, Grant S, Dent P. Bareford MD, et al. Among authors: poklepovic a. Cancer Biol Ther. 2012 Jul;13(9):793-803. doi: 10.4161/cbt.20562. Epub 2012 Jun 7. Cancer Biol Ther. 2012. PMID: 22673740 Free PMC article.
Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy.
Cruickshanks N, Hamed HA, Booth L, Tavallai S, Syed J, Sajithlal GB, Grant S, Poklepovic A, Dent P. Cruickshanks N, et al. Among authors: poklepovic a. Cancer Biol Ther. 2013 Oct 1;14(10):982-96. doi: 10.4161/cbt.26234. Epub 2013 Aug 22. Cancer Biol Ther. 2013. PMID: 24025251 Free PMC article.
Pazopanib and HDAC inhibitors interact to kill sarcoma cells.
Tavallai S, Hamed HA, Grant S, Poklepovic A, Dent P. Tavallai S, et al. Among authors: poklepovic a. Cancer Biol Ther. 2014 May;15(5):578-85. doi: 10.4161/cbt.28163. Epub 2014 Feb 20. Cancer Biol Ther. 2014. PMID: 24556916 Free PMC article.
108 results