Pegan SD - Search Results

1

Engineering the Organophosphorus Acid Anhydrolase Enzyme for Increased Catalytic Efficiency and Broadened Stereospecificity on Russian VX.

Daczkowski CM, Pegan SD, Harvey SP. Daczkowski CM, et al. Among authors: pegan sd. Biochemistry. 2015 Oct 20;54(41):6423-33. doi: 10.1021/acs.biochem.5b00624. Epub 2015 Oct 6. Biochemistry. 2015. PMID: 26418828

2

Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis.

Pegan SD, Rukseree K, Capodagli GC, Baker EA, Krasnykh O, Franzblau SG, Mesecar AD. Pegan SD, et al. Biochemistry. 2013 Feb 5;52(5):912-25. doi: 10.1021/bi300928u. Epub 2013 Jan 18. Biochemistry. 2013. PMID: 23298222 Free PMC article.

3

Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase.

Zhai X, Go MK, O'Donoghue AC, Amyes TL, Pegan SD, Wang Y, Loria JP, Mesecar AD, Richard JP. Zhai X, et al. Among authors: pegan sd. Biochemistry. 2014 Jun 3;53(21):3486-501. doi: 10.1021/bi500458t. Epub 2014 May 22. Biochemistry. 2014. PMID: 24825099 Free PMC article.

4

Structural and functional characterization of methicillin-resistant Staphylococcus aureus's class IIb fructose 1,6-bisphosphate aldolase.

Capodagli GC, Lee SA, Boehm KJ, Brady KM, Pegan SD. Capodagli GC, et al. Among authors: pegan sd. Biochemistry. 2014 Dec 9;53(48):7604-14. doi: 10.1021/bi501141t. Epub 2014 Nov 21. Biochemistry. 2014. PMID: 25390935 Free PMC article.

5

Biochemical and Structural Insights into the Preference of Nairoviral DeISGylases for Interferon-Stimulated Gene Product 15 Originating from Certain Species.

Deaton MK, Dzimianski JV, Daczkowski CM, Whitney GK, Mank NJ, Parham MM, Bergeron E, Pegan SD. Deaton MK, et al. Among authors: pegan sd. J Virol. 2016 Aug 26;90(18):8314-27. doi: 10.1128/JVI.00975-16. Print 2016 Sep 15. J Virol. 2016. PMID: 27412597 Free PMC article.

6

Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.

Daczkowski CM, Dzimianski JV, Clasman JR, Goodwin O, Mesecar AD, Pegan SD. Daczkowski CM, et al. Among authors: pegan sd. J Mol Biol. 2017 Jun 2;429(11):1661-1683. doi: 10.1016/j.jmb.2017.04.011. Epub 2017 Apr 21. J Mol Biol. 2017. PMID: 28438633 Free PMC article.

7

Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.

Daczkowski CM, Goodwin OY, Dzimianski JV, Farhat JJ, Pegan SD. Daczkowski CM, et al. Among authors: pegan sd. J Virol. 2017 Nov 14;91(23):e01067-17. doi: 10.1128/JVI.01067-17. Print 2017 Dec 1. J Virol. 2017. PMID: 28931677 Free PMC article.

8

Insights into the Porcine Reproductive and Respiratory Syndrome Virus Viral Ovarian Tumor Domain Protease Specificity for Ubiquitin and Interferon Stimulated Gene Product 15.

Bester SM, Daczkowski CM, Faaberg KS, Pegan SD. Bester SM, et al. Among authors: pegan sd. ACS Infect Dis. 2018 Sep 14;4(9):1316-1326. doi: 10.1021/acsinfecdis.8b00068. Epub 2018 Jun 12. ACS Infect Dis. 2018. PMID: 29856201 Free PMC article.

9

Structural Insights of Stereospecific Inhibition of Human Acetylcholinesterase by VX and Subsequent Reactivation by HI-6.

Bester SM, Guelta MA, Cheung J, Winemiller MD, Bae SY, Myslinski J, Pegan SD, Height JJ. Bester SM, et al. Among authors: pegan sd. Chem Res Toxicol. 2018 Dec 17;31(12):1405-1417. doi: 10.1021/acs.chemrestox.8b00294. Epub 2018 Dec 4. Chem Res Toxicol. 2018. PMID: 30462502 Free article.

10

Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.

Dzimianski JV, Beldon BS, Daczkowski CM, Goodwin OY, Scholte FEM, Bergeron É, Pegan SD. Dzimianski JV, et al. Among authors: pegan sd. PLoS Pathog. 2019 Jan 10;15(1):e1007515. doi: 10.1371/journal.ppat.1007515. eCollection 2019 Jan. PLoS Pathog. 2019. PMID: 30629698 Free PMC article.

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