A novel first primary anchor extends the MHC class II I-Ad binding motif to encompass nine amino acids.
Bartnes K, Leon F, Briand JP, Travers PJ, Hannestad K.
Bartnes K, et al.
Int Immunol. 1997 Aug;9(8):1185-93. doi: 10.1093/intimm/9.8.1185.
Int Immunol. 1997.
PMID: 9263016
However, the lysine of gamma 2aa at P9 impairs binding to I-Ad, which may explain why the gamma 2ab allopeptide-reactive T cells escaped negative selection. The data rationalize our observation (Bartnes, K. and Hannestad, K. 1997. Eur. J. Immunol. 27:1124) th …
However, the lysine of gamma 2aa at P9 impairs binding to I-Ad, which may explain why the gamma 2ab allopeptide-reactive T cells escaped neg …