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The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence.
Thompson KN, Whipple RA, Yoon JR, Lipsky M, Charpentier MS, Boggs AE, Chakrabarti KR, Bhandary L, Hessler LK, Martin SS, Vitolo MI. Thompson KN, et al. Among authors: whipple ra. Oncotarget. 2015 Nov 3;6(34):35231-46. doi: 10.18632/oncotarget.6159. Oncotarget. 2015. PMID: 26497685 Free PMC article.
c-Src differentially regulates the functions of microtentacles and invadopodia.
Balzer EM, Whipple RA, Thompson K, Boggs AE, Slovic J, Cho EH, Matrone MA, Yoneda T, Mueller SC, Martin SS. Balzer EM, et al. Among authors: whipple ra. Oncogene. 2010 Dec 2;29(48):6402-8. doi: 10.1038/onc.2010.360. Epub 2010 Oct 18. Oncogene. 2010. PMID: 20956943 Free PMC article.
22 results