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Synthesis, binding affinity, radiolabeling, and microPET evaluation of 4-(2-substituted-4-substituted)-8-(dialkylamino)-6-methyl-1-substituted-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-ones as ligands for brain corticotropin-releasing factor type-1 (CRF1) receptors.
Stehouwer JS, Bourke CH, Owens MJ, Voll RJ, Kilts CD, Goodman MM. Stehouwer JS, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5111-4. doi: 10.1016/j.bmcl.2015.10.010. Epub 2015 Oct 8. Bioorg Med Chem Lett. 2015. PMID: 26456805 Free PMC article.
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 (N-fluoroalkyl) labeled 2beta-carbomethoxy-3beta-(4'-(3-furyl)phenyl)tropanes and -nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.
Stehouwer JS, Plisson C, Jarkas N, Zeng F, Voll RJ, Williams L, Martarello L, Votaw JR, Tamagnan G, Goodman MM. Stehouwer JS, et al. J Med Chem. 2005 Nov 3;48(22):7080-3. doi: 10.1021/jm0504095. J Med Chem. 2005. PMID: 16250668
Synthesis, radiosynthesis, and biological evaluation of fluorine-18-labeled 2beta-carbo(fluoroalkoxy)-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.
Stehouwer JS, Jarkas N, Zeng F, Voll RJ, Williams L, Camp VM, Malveaux EJ, Votaw JR, Howell L, Owens MJ, Goodman MM. Stehouwer JS, et al. J Med Chem. 2008 Dec 25;51(24):7788-99. doi: 10.1021/jm800781a. J Med Chem. 2008. PMID: 19053782 Free PMC article.
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter.
Zeng F, Mun J, Jarkas N, Stehouwer JS, Voll RJ, Tamagnan GD, Howell L, Votaw JR, Kilts CD, Nemeroff CB, Goodman MM. Zeng F, et al. Among authors: stehouwer js. J Med Chem. 2009 Jan 8;52(1):62-73. doi: 10.1021/jm800817h. J Med Chem. 2009. PMID: 19067522 Free PMC article.
Synthesis, fluorine-18 radiolabeling, and biological evaluation of N-((E)-4-fluorobut-2-en-1-yl)-2beta-carbomethoxy-3beta-(4'-halophenyl)nortropanes: candidate radioligands for in vivo imaging of the brain dopamine transporter with positron emission tomography.
Stehouwer JS, Daniel LM, Chen P, Voll RJ, Williams L, Plott SJ, Votaw JR, Owens MJ, Howell L, Goodman MM. Stehouwer JS, et al. J Med Chem. 2010 Aug 12;53(15):5549-57. doi: 10.1021/jm100269c. J Med Chem. 2010. PMID: 20597489 Free PMC article.
31 results