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Excess TGF-β mediates muscle weakness associated with bone metastases in mice.
Waning DL, Mohammad KS, Reiken S, Xie W, Andersson DC, John S, Chiechi A, Wright LE, Umanskaya A, Niewolna M, Trivedi T, Charkhzarrin S, Khatiwada P, Wronska A, Haynes A, Benassi MS, Witzmann FA, Zhen G, Wang X, Cao X, Roodman GD, Marks AR, Guise TA. Waning DL, et al. Among authors: roodman gd. Nat Med. 2015 Nov;21(11):1262-1271. doi: 10.1038/nm.3961. Epub 2015 Oct 12. Nat Med. 2015. PMID: 26457758 Free PMC article.
Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma.
Delgado-Calle J, Anderson J, Cregor MD, Hiasa M, Chirgwin JM, Carlesso N, Yoneda T, Mohammad KS, Plotkin LI, Roodman GD, Bellido T. Delgado-Calle J, et al. Among authors: roodman gd. Cancer Res. 2016 Mar 1;76(5):1089-100. doi: 10.1158/0008-5472.CAN-15-1703. Epub 2016 Feb 1. Cancer Res. 2016. PMID: 26833121 Free PMC article.
Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo.
Teramachi J, Silbermann R, Yang P, Zhao W, Mohammad KS, Guo J, Anderson JL, Zhou D, Feng R, Myint KZ, Maertz N, Beumer JH, Eiseman JL, Windle JJ, Xie XQ, Roodman GD, Kurihara N. Teramachi J, et al. Among authors: roodman gd. Leukemia. 2016 Feb;30(2):390-8. doi: 10.1038/leu.2015.229. Epub 2015 Aug 19. Leukemia. 2016. PMID: 26286116 Free PMC article.
Cytokine regulation of bone cell differentiation.
Alsina M, Guise TA, Roodman GD. Alsina M, et al. Among authors: roodman gd. Vitam Horm. 1996;52:63-98. doi: 10.1016/s0083-6729(08)60407-0. Vitam Horm. 1996. PMID: 8909157 Review.
Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference.
Lipton A, Berenson JR, Body JJ, Boyce BF, Bruland OS, Carducci MA, Cleeland CS, Clohisy DR, Coleman RE, Cook RJ, Guise TA, Pearse RN, Powles TJ, Rogers MJ, Roodman GD, Smith MR, Suva LJ, Vessella RL, Weilbaecher KN, King L. Lipton A, et al. Among authors: roodman gd. Clin Cancer Res. 2006 Oct 15;12(20 Pt 2):6209s-6212s. doi: 10.1158/1078-0432.CCR-06-1213. Clin Cancer Res. 2006. PMID: 17062702 Free PMC article.
Metastasis and bone loss: advancing treatment and prevention.
Coleman RE, Lipton A, Roodman GD, Guise TA, Boyce BF, Brufsky AM, Clézardin P, Croucher PI, Gralow JR, Hadji P, Holen I, Mundy GR, Smith MR, Suva LJ. Coleman RE, et al. Among authors: roodman gd. Cancer Treat Rev. 2010 Dec;36(8):615-20. doi: 10.1016/j.ctrv.2010.04.003. Epub 2010 May 15. Cancer Treat Rev. 2010. PMID: 20478658 Free PMC article. Review.
Multiple Myeloma and Bone: The Fatal Interaction.
Marino S, Roodman GD. Marino S, et al. Among authors: roodman gd. Cold Spring Harb Perspect Med. 2018 Aug 1;8(8):a031286. doi: 10.1101/cshperspect.a031286. Cold Spring Harb Perspect Med. 2018. PMID: 29229668 Free PMC article. Review.
Therapeutic targets in myeloma bone disease.
Marino S, Petrusca DN, Roodman GD. Marino S, et al. Among authors: roodman gd. Br J Pharmacol. 2021 May;178(9):1907-1922. doi: 10.1111/bph.14889. Epub 2020 Feb 3. Br J Pharmacol. 2021. PMID: 31647573 Free article. Review.
297 results