Hay M - Search Results

1

Mono-Oxidation of Bidentate Bis-phosphines in Catalyst Activation: Kinetic and Mechanistic Studies of a Pd/Xantphos-Catalyzed C-H Functionalization.

Ji Y, Plata RE, Regens CS, Hay M, Schmidt M, Razler T, Qiu Y, Geng P, Hsiao Y, Rosner T, Eastgate MD, Blackmond DG. Ji Y, et al. Among authors: hay m. J Am Chem Soc. 2015 Oct 21;137(41):13272-81. doi: 10.1021/jacs.5b01913. Epub 2015 Oct 13. J Am Chem Soc. 2015. PMID: 26461028

2

C-H Arylation in the Formation of a Complex Pyrrolopyridine, the Commercial Synthesis of the Potent JAK2 Inhibitor, BMS-911543.

Fox RJ, Cuniere NL, Bakrania L, Wei C, Strotman NA, Hay M, Fanfair D, Regens C, Beutner GL, Lawler M, Lobben P, Soumeillant MC, Cohen B, Zhu K, Skliar D, Rosner T, Markwalter CE, Hsiao Y, Tran K, Eastgate MD. Fox RJ, et al. Among authors: hay m. J Org Chem. 2019 Apr 19;84(8):4661-4669. doi: 10.1021/acs.joc.8b02383. Epub 2018 Nov 12. J Org Chem. 2019. PMID: 30388009

3

One-electron reduction potential of the neutral guanyl radical in the GC base pair of duplex DNA.

Shinde SS, Maroz A, Hay MP, Anderson RF. Shinde SS, et al. J Am Chem Soc. 2009 Apr 15;131(14):5203-7. doi: 10.1021/ja8087339. J Am Chem Soc. 2009. PMID: 19320486 Free PMC article.

4

Spin trapping of radicals other than the *OH radical upon reduction of the anticancer agent tirapazamine by cytochrome P450 reductase.

Shinde SS, Hay MP, Patterson AV, Denny WA, Anderson RF. Shinde SS, et al. J Am Chem Soc. 2009 Oct 14;131(40):14220-1. doi: 10.1021/ja906860a. J Am Chem Soc. 2009. PMID: 19772319

5

Characterization of radicals formed following enzymatic reduction of 3-substituted analogues of the hypoxia-selective cytotoxin 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).

Shinde SS, Maroz A, Hay MP, Patterson AV, Denny WA, Anderson RF. Shinde SS, et al. J Am Chem Soc. 2010 Mar 3;132(8):2591-9. doi: 10.1021/ja908689f. J Am Chem Soc. 2010. PMID: 20141134

6

Oxidation of 2-deoxyribose by benzotriazinyl radicals of antitumor 3-amino-1,2,4-benzotriazine 1,4-dioxides.

Shinde SS, Anderson RF, Hay MP, Gamage SA, Denny WA. Shinde SS, et al. J Am Chem Soc. 2004 Jun 30;126(25):7865-74. doi: 10.1021/ja048740l. J Am Chem Soc. 2004. PMID: 15212534

7

Activation of 3-amino-1,2,4-benzotriazine 1,4-dioxide antitumor agents to oxidizing species following their one-electron reduction.

Anderson RF, Shinde SS, Hay MP, Gamage SA, Denny WA. Anderson RF, et al. J Am Chem Soc. 2003 Jan 22;125(3):748-56. doi: 10.1021/ja0209363. J Am Chem Soc. 2003. PMID: 12526674

8

Potentiation of the cytotoxicity of the anticancer agent tirapazamine by benzotriazine N-oxides: the role of redox equilibria.

Anderson RF, Shinde SS, Hay MP, Denny WA. Anderson RF, et al. J Am Chem Soc. 2006 Jan 11;128(1):245-9. doi: 10.1021/ja0559101. J Am Chem Soc. 2006. PMID: 16390153

9

Radical Chemistry and Cytotoxicity of Bioreductive 3-Substituted Quinoxaline Di-N-Oxides.

Anderson RF, Yadav P, Shinde SS, Hong CR, Pullen SM, Reynisson J, Wilson WR, Hay MP. Anderson RF, et al. Among authors: hay mp. Chem Res Toxicol. 2016 Aug 15;29(8):1310-24. doi: 10.1021/acs.chemrestox.6b00133. Epub 2016 Jul 29. Chem Res Toxicol. 2016. PMID: 27380897

10

Characterisation of enzyme prodrug gene therapy combinations in coated spheroids and vascular networks in vitro.

Hunt MA, Li D, Hay MP, Currie MJ, Robinson BA, Patterson AV, Dachs GU. Hunt MA, et al. J Gene Med. 2012 Jan;14(1):62-74. doi: 10.1002/jgm.1635. J Gene Med. 2012. PMID: 22147660

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